| 1549703-29-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• CAS: 1549703-29-8
• 化学式: C₃₅H₃₂N₃RhS₂
• 分子量: 661.697
• InChiKey: PYSUDMFRVDKLPJ-UHFFFAOYSA-M

反应信息

• 作为产物：
  描述：

  4-benzylpiperidine-1-carbothioic acid 、 [Rh(2-C₆H₄py)₂Cl]₂*1/4CH₂Cl₂ 以 二甲基亚砜 、 乙腈 为溶剂， 反应 12.0h， 以73%的产率得到
  参考文献：
  名称：

  Cyclometalated rhodium(III) complexes bearing dithiocarbamate derivative: Synthesis, characterization, interaction with DNA and biological study

  摘要：

  Reaction of three different dithiocarbamates (4-MePipzcdtH, (LH)-H-1; MorphcdtH, (LH)-H-2 and 4-BzPipercdtH, (LH)-H-3) with [Rh(2-C(6)H(4)py)(2)Cl](2)center dot 1/4CH(2)Cl(2) afforded a class of rhodium(III) complexes of the type [Rh-III(2-C(6)H(4)py)(2)(L)]. The complexes were fully characterized by several spectroscopic tools along with a detailed structural characterization of [Rh(2-C(6)H(4)py)2(L-1)] (1) by single crystal X-ray diffraction. Structural analysis of 1 showed a distorted octahedron in which both of the 2-phenylpyridyl nitrogens are in axial positions, trans to one another and the sulfur atoms are opposite to the phenyl rings. Electrochemical analysis by cyclic voltammetry reveals irreversible redox behavior of the rhodium centre in 1,2 and 3. Their DNA binding ability have been also evaluated from the absorption spectral study as well as fluorescence quenching properties, suggesting the intercalative interaction of the complexes with CT-DNA due to the stacking between the aromatic chromophore and the base pairs of DNA. Antibacterial activity of complexes has also been studied by agar disc diffusion method against some species of pathogenic bacteria (Escherichia coli, Vibrio cholerae, Streptococcus pneumonia and Bacillus cereus). (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2013.11.028