cyclobutyl iodomethylcarbonate | 1259435-99-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: cyclobutyl iodomethylcarbonate
• 英文别名: Cyclobutyl iodomethyl carbonate
• CAS: 1259435-99-8
• 化学式: C₆H₉IO₃
• 分子量: 256.04
• InChiKey: JZSPQWCTACNPHJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• NOVEL COMPOUNDS, THEIR PREPARATION AND THEIR USES
  申请人：Inhibikase Therapeutics, Inc.

  公开号：US20140100225A1

  公开（公告）日：2014-04-10

  Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.

  小说化合物及其合成已被描述。还描述了在预防或治疗受试者中的癌症、细菌感染或病毒感染中使用这些化合物的方法。
• N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE
  申请人：Suetsugu Satoshi

  公开号：US20120122773A1

  公开（公告）日：2012-05-17

  The present invention provides a compound of formula (I): wherein R 1a is optionally substituted C 1-6 alkyl, etc.; R 1m is hydrogen atom, etc.; G 1 , G 2 , G 3 and G 4 are (i), etc. ((i) G 1 is —N(R 1b )—, G 2 is —CO—, G 3 is —C(R 1c )(R 1d )—, and G 4 is oxygen, etc.); R 1b is optionally substituted C 1-6 alkyl, etc.; R 1c and R 1d are each independently optionally substituted C 1-6 alkyl, etc.; R 2 is optionally substituted C 1-6 alkyl, etc.; R 3a , R 3b , R 3c and R 3d are each independently a group: -A-B (A is a single bond, etc., B is hydrogen atom, etc.), etc.; n is 1, etc.; R 5 is C 1-4 alkoxycarbonyl, etc., or a pharmaceutically acceptable salt thereof, which is useful as a renin inhibitor.

  本发明提供了一种化合物，其化学式为(I)：其中R1a是可选取代的C1-6烷基等；R1m是氢原子等；G1，G2，G3和G4是(i)等，((i) G1是—N(R1b)—，G2是—CO—，G3是—C(R1c)(R1d)—，G4是氧原子等)；R1b是可选取代的C1-6烷基等；R1c和R1d分别独立地是可选取代的C1-6烷基等；R2是可选取代的C1-6烷基等；R3a、R3b、R3c和R3d分别独立地是一种基团：-A-B（其中A是单键等，B是氢原子等）等；n是1等；R5是C1-4烷氧羰基等，或其药学上可接受的盐，其作为一种肾素抑制剂是有用的。
• Methods of Treating Tumoral Diseases, or Bacterial or Viral Infections
  申请人：Deokar Rhushikesh Chandrabhan

  公开号：US20170000789A1

  公开（公告）日：2017-01-05

  Novel compounds and their synthesis are described. Methods for using these compounds in the prevention or treatment of cancer, a bacterial infection or a viral infection in a subject are also described.
• US8658639B2
  申请人：——

  公开号：US8658639B2

  公开（公告）日：2014-02-25
• US9487500B2
  申请人：——

  公开号：US9487500B2

  公开（公告）日：2016-11-08