N-methyl-3-[(5,5,6,6,6-pentafluorohexyl)sulphonyl]propan-1-amine | 1353009-27-4

• 分子结构分类: 有机化合物 - 有机硫化合物 - 磺酰类
• 英文名称: N-methyl-3-[(5,5,6,6,6-pentafluorohexyl)sulphonyl]propan-1-amine
• 英文别名: N-methyl-3-(5,5,6,6,6-pentafluorohexylsulfonyl)propan-1-amine
• CAS: 1353009-27-4
• 化学式: C₁₀H₁₈F₅NO₂S
• 分子量: 311.316
• InChiKey: RZNBGMUHRWRMIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS
  申请人：Wintermantel Tim

  公开号：US20130252890A1

  公开（公告）日：2013-09-26

  The invention relates to selective oestrogen receptor modulators (SERM) and methods of production thereof, use thereof for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular of bleeding disorders, osteoporosis, endometriosis, myomata, hormone-dependent tumours, for hormone replacement therapy and for contraception.

  该发明涉及选择性雌激素受体调节剂（SERM）及其生产方法，以及将其用于治疗和/或预防疾病以及将其用于生产用于治疗和/或预防疾病的药物产品，特别是用于出血性疾病、骨质疏松症、子宫内膜异位症、子宫肌瘤、激素依赖性肿瘤、激素替代疗法和避孕。
• 6,7-DIHYDRO-5H-BENZO[7]ANNULEN-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG, PHARMAZEUTISCHE PRÄPARATE DIE DIESE ENTHALTEN, SOWIE DEREN VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN
  申请人：Bayer Intellectual Property GmbH

  公开号：EP2585435A1

  公开（公告）日：2013-05-01
• IRIDIUM-CONTAINING ORGANIC ELECTROLUMINESCENT MATERIAL, PREPARATION METHOD AND ORGANIC ELECTROLUMINESCENT DEVICE THEREOF
  申请人：Zhou Mingjie

  公开号：US20130253198A1

  公开（公告）日：2013-09-26

  The invention provides an iridium-containing organic electroluminescent material, the formula of which is H: wherein R is C 1 -C 8 alkyl. The molecule of the iridium-containing organic electroluminescent material contains benzimidazole group with electron transmission function and the benzimidazole has alkyl and fluorobenzyl group, which can improve the electron injection and transmission function of the electroluminescent material, and enable the electroluminescent material to have higher internal quanta efficiency and electroluminescent efficiency. The invention also provides a preparation method of the iridium-containing organic electroluminescent material, and an organic electroluminescent device using the material.
• [DE] 6,7-DIHYDRO-5H-BENZO[7]ANNULEN-DERIVATE, VERFAHREN ZU IHRER HERSTELLUNG, PHARMAZEUTISCHE PRÄPARATE DIE DIESE ENTHALTEN, SOWIE DEREN VERWENDUNG ZUR HERSTELLUNG VON ARZNEIMITTELN<br/>[EN] 6,7-DIHYDRO-5H-BENZO[7]ANNULENE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, PHARMACEUTICAL PREPARATIONS COMPRISING THEM, AND THE USE THEREOF FOR PRODUCTION OF MEDICAMENTS<br/>[FR] DÉRIVÉS DE 6,7-DIHYDRO-5H-BENZO[7]ANNULÈNE, LEUR PROCÉDÉ DE PRÉPARATION, PRÉPARATIONS PHARMACEUTIQUES LES CONTENANT ET LEUR UTILISATION POUR LA FABRICATION DE PRODUITS PHARMACEUTIQUES
  申请人：BAYER PHARMA AG

  公开号：WO2011161101A1

  公开（公告）日：2011-12-29

  Die Erfindung betrifft selektive Estrogen Receptor Modulatoren (SERM) und Verfahren zu ihrer Herstellung, ihre Verwendung zur Behandlung und/oder Prophylaxe von Krankheiten sowie ihre Verwendung zur Herstellung von Arzneimitteln zur Behandlung und/oder Prophylaxe von Krankheiten, insbesondere von Blutungsbeschwerden, Osteoporose, Endometriose, Myomen, hormonabhängigen Tumoren, zur Hormonersatztherapie und zur Kontrazeption.