1-acetyl-4-(6-{2-[3-(chloromethyl)phenyl]ethyl}pyridin-3-yl)piperazine | 1197295-08-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-acetyl-4-(6-{2-[3-(chloromethyl)phenyl]ethyl}pyridin-3-yl)piperazine
• 英文别名: 1-[4-[6-[2-[3-(Chloromethyl)phenyl]ethyl]pyridin-3-yl]piperazin-1-yl]ethanone
• CAS: 1197295-08-1
• 化学式: C₂₀H₂₄ClN₃O
• 分子量: 357.883
• InChiKey: HTSGJSUZDWIORK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  25
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  36.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR<br/>[FR] DÉRIVÉ DE BENZÈNE OU DE THIOPHÈNE ET SON UTILISATION EN TANT QU'INHIBITEUR DE LA VAP-1
  申请人：R TECH UENO LTD

  公开号：WO2009145360A1

  公开（公告）日：2009-12-03

  The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof.

  本发明提供了一种新颖的苯衍生物或噻吩衍生物，可用作VAP-1抑制剂，或用作预防或治疗与VAP-1相关的疾病等的药物，即由以下式（I）表示的化合物：其中每个符号如本说明书中所定义，或其药学上可接受的盐。
• NOVEL HETEROCYCLIC COMPOUNDS AS PESTICIDES
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：US20200062729A1

  公开（公告）日：2020-02-27

  The invention relates to novel compounds of the formula (I) in which Z, Y, A 1 , A 2 , A 3 , A 4 , X, R 7 , R 8 and R 9 have the meanings mentioned above, and processes and intermediates for the preparation thereof, and their use for controlling animal pests, in particular insects.

  该发明涉及公式（I）中的新化合物，其中Z、Y、A1、A2、A3、A4、X、R7、R8和R9具有上述提及的含义，以及其制备的过程和中间体，以及它们用于控制动物害虫，特别是昆虫。
• BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR
  申请人：Matsukawa Tatsuya

  公开号：US20110059957A1

  公开（公告）日：2011-03-10

  The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I): wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof.

  本发明提供了一种新型苯并衍生物或噻吩衍生物，可用作VAP-1抑制剂，或用作预防或治疗VAP-1相关疾病等药物，即由公式（I）表示的化合物：其中每个符号如本说明书所定义，或其药学上可接受的盐。
• Benzene or thiophene derivative and use thereof as VAP-1 inhibitor
  申请人：R-Tech Ueno, Ltd.

  公开号：EP2886534A1

  公开（公告）日：2015-06-24

  The present invention provides a novel benzene derivative or thiophene derivative useful as a VAP-1 inhibitor, or a medicament for the prophylaxis or treatment of a VAP-1 associated disease and the like, namely, a compound represented by the formula (I) : wherein each symbol is as defined in the present specification, or a pharmaceutically acceptable salt thereof.

  本发明提供了一种新型苯衍生物或噻吩衍生物，可用作 VAP-1 抑制剂或预防或治疗 VAP-1 相关疾病等的药物，即由式 (I) 所代表的化合物： 其中各符号如本说明书所定义，或其药学上可接受的盐。
• 2-{[2-(PHENYLOXYMETHYL)PYRIDIN-5-YL]OXY}-ETHANAMIN-DERIVATE UND VERWANDTE VERBINDUNGEN ALS SCHÄDLINGSBEKÄMPFUNGSMITTEL Z.B. FÜR DEN PFLANZENSCHUTZ
  申请人：Bayer CropScience Aktiengesellschaft

  公开号：EP3619196B1

  公开（公告）日：2022-03-30