1-(4-(4-methylpiperazine-1-yl)tetrahydrofuran-3-yl)-1H-tetrazole-5-thiol | 1337928-79-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 1-(4-(4-methylpiperazine-1-yl)tetrahydrofuran-3-yl)-1H-tetrazole-5-thiol
• 英文别名: 1-[4-(4-methylpiperazin-1-yl)oxolan-3-yl]-2H-tetrazole-5-thione
• CAS: 1337928-79-6
• 化学式: C₁₀H₁₈N₆OS
• 分子量: 270.359
• InChiKey: OXKUIABPBVMVNL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  87.8
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] NOVEL QUINOXALINE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS DE QUINOXALINE
  申请人：DONG A PHARM CO LTD

  公开号：WO2011122815A2

  公开（公告）日：2011-10-06

  This invention relates to a novel compound represented by the following Chemical Formula 1, a process for preparing it, and its pharmaceutically approved salt comprising it as an active ingredient. The compound of this invention is GLP 1 receptor regulating low molecular weight compound useful for treatment of metabolic diseases such as diabetes and obesity by regulating the function of glucagon like peptide 1 receptor (GLP 1 receptor) for the disease or disorder carried by GLP 1 since it has the effects on a drop of blood sugar and an improvement of insulin resistance.