1-(1-propyl-hept-2-ynyl)-piperidine | 94027-79-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-(1-propyl-hept-2-ynyl)-piperidine
• 英文别名: 1-<1-Propyl-3-butyl-2-propin-1-yl>-piperidin
• CAS: 94027-79-9
• 化学式: C₁₅H₂₇N
• 分子量: 221.386
• InChiKey: DZGPULMIDDGQRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.83
• 重原子数：
  16.0
• 可旋转键数：
  5.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.87
• 拓扑面积：
  3.24
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  哌啶 、 正丁醛 、 1-己炔 在 Ag/Ni-MOF 作用下， 以 乙腈 为溶剂， 反应 2.0h， 以84%的产率得到1-(1-propyl-hept-2-ynyl)-piperidine
  参考文献：
  名称：

  Silver Nanoparticles Supported by Novel Nickel Metal-Organic Frameworks: An Efficient Heterogeneous Catalyst for an A³ Coupling Reaction

  摘要：

  一种新型的银纳米粒子异质催化剂通过使用镍金属有机框架（Ni-MOF）作为模板制备。该催化剂在A³偶联反应中对线性脂肪醛具有非常高的催化活性和严格的结构选择性。催化剂可以通过简单的相分离进行回收，且多次重复使用后活性没有明显下降。

  DOI：

  10.1055/s-0028-1087540

文献信息

• Mesoporous SBA-15 supported silver nanoparticles as environmentally friendly catalysts for three-component reaction of aldehydes, alkynes and amines with glycol as a “green” solvent
  作者：Guo-Ping Yong、Dong Tian、Hong-Wu Tong、Shao-Min Liu

  DOI：10.1016/j.molcata.2010.03.007

  日期：2010.5.17

  The mesoporous SBA-15 supported silver nanoparticles catalyst system with a highly ordered hexagonal mesostructure was prepared by an in situ reduction method using hexamethylenetetramine as mild and efficient reducing agent. These AgSBA-15 materials act as environmentally friendly catalysts in A(3)-coupling reactions of aldehydes, amines, and terminal alkynes with glycol as a "green" solvent. It is also found that the maximum reaction yield has been obtained for an average Ag-nanoparticle size of about 8 nm. The catalyst could also be recovered easily and used repetitively four times without significantly affecting the catalytic activity. The heterogeneous catalysts were fully characterized by N-2 adsorption and desorption, XRD, TEM, ICP and XPS. (C) 2010 Elsevier B.V. All rights reserved.
• Immobilized silver on surface-modified ZnO nanoparticles: As an efficient catalyst for synthesis of propargylamines in water
  作者：Farnaz Movahedi、Hassan Masrouri、M.Z. Kassaee

  DOI：10.1016/j.molcata.2014.08.007

  日期：2014.12

  Silver nanoparticles were immobilized on ionic liquid modified zinc oxide nanoparticles leading to a ZnO-IL/Ag NPs catalyst, which exhibits high catalytic performance in the synthesis of propargylamines through one-pot three-component condensation reaction of aldehydes, amines, and alkynes in water. The as-prepared catalyst was characterized by ICP-AES, FT-IR, XRD, SEM, and TEM. The catalyst was easily recycled and reused at least five times without significant loss of its catalytic activity. (C) 2014 Elsevier B.V. All rights reserved.