{2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazole-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-yl}-(4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl)-methanone | 1421503-09-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: {2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazole-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-yl}-(4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl)-methanone
• 英文别名: {2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridin-5-yl}-(4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl)-methanone；{2-[6-(2-ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-1,4,6,7-tetrahydro-imidazolo[4,5-c]pyridin-5-yl}-(4-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazin-5'-yl)-methanone；[2-[6-(2-ethyl-5-fluoro-4-hydroxyphenyl)-1H-indazol-3-yl]-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-5-yl]-[5-(4-methylpiperazin-1-yl)pyrazin-2-yl]methanone
• CAS: 1421503-09-4
• 化学式: C₃₁H₃₂FN₉O₂
• 分子量: 581.653
• InChiKey: FJRQBRCNNRQJHC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  43
• 可旋转键数：
  5
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  130
• 氢给体数：
  3
• 氢受体数：
  9

文献信息

• INDAZOLES
  申请人：Pfizer Limited

  公开号：EP2736907B1

  公开（公告）日：2015-10-07