| 1615224-31-1

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• CAS: 1615224-31-1
• 化学式: C₁₈H₂₇N₃O₃Si
• 分子量: 361.516
• InChiKey: PWYDLPHGAGITSQ-UHFFFAOYSA-N

物化性质

• 沸点：
  403.0±40.0 °C(Predicted)
• 密度：
  1.093±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.75
• 重原子数：
  25.0
• 可旋转键数：
  11.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  56.71
• 氢给体数：
  0.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  二甲基吡啶胺 、 3-碘苯基三甲氧基硅烷 在 三乙胺 作用下， 以 甲苯 为溶剂， 反应 16.0h， 以90%的产率得到
  参考文献：
  名称：

  Delivery modulation in silica mesoporous supports via functionalization in the pore outlets with a Zn(II)–bis(2-pyridylmethyl)amine complex

  摘要：

  This paper focuses on the study of the release behaviour of an entrapped dye (i.e. [Ru(bipy)(3)](2+)) in the presence of different anions from silica mesoporous supports functionalized in the external surface with Zn(II)-bis(2-pyridylmethyl)amine complexes (solid SZn). The Zn(II)-dipicolylamine complexes, anchored in the external surface of SZn, are too small to induce pore blockage and the loaded [Ru(bipy)(3)](2+) dye is freely to diffuse from the inner of the pores to the bulk solution. Addition of selected anions (F, Cl, Br, I, AcO, BzO, SO42, NO3, PO43, P2O72, ATP, ADP and AMP) modulates the release of the entrapped cargo. It was observed that the interaction of the Zn(II) complex with bulky organic phosphates (such as ATP, ADP and AMP), pyrophosphate and phosphate resulted in a remarkable inhibition of the [Ru(bipy)(3)](2+) dye. Small or poorly coordinating anions induced moderate or negligible inhibitions of [Ru(bipy)(3)](2+) release. The delivery observed was clearly related with the ability of the anion to form complexes with the Zn(II)-dipicolylamine groups and with the size and charge of the anion. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2014.01.036