(2,2,2-trideuterio-ethyl)-lithium | 1629-54-5

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: (2,2,2-trideuterio-ethyl)-lithium
• 英文别名: 2,2,2-Trideuteroethyllithium
• CAS: 1629-54-5
• 化学式: C₂H₅*Li
• 分子量: 38.9789
• InChiKey: BLHLJVCOVBYQQS-MUTAZJQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.59
• 重原子数：
  3.0
• 可旋转键数：
  1.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  0.0

反应信息

• 作为反应物：
  描述：

  trans-chloro(triphenylsilyl)bis(dimethylphenylphosphine)platinum(II) 、 (2,2,2-trideuterio-ethyl)-lithium 以 四氢呋喃 、 正戊烷 为溶剂， 以69%的产率得到cis-Pt(PMe2Ph)2(SiPh3)CH2CD3
  参考文献：
  名称：

  Thermolysis Reactions of cis-PtR(SiPh₃)(PMe₂Ph)₂ in Solution

  摘要：

  A series of trans- and cis-PtR(SiPh3)(PMe2Ph)(2) complexes have been prepared and their thermolysis reactions in solution examined. The trans isomers (R = Me, Et) are robust, and only the methyl complex affords MeSiPh3 as the reductive elimination product in 72-82% yields. In contrast, the cis isomers (R = Me, Et, Pr, Bu) form the corresponding alkylsilanes in almost quantitative yields (>97%). Despite the selective formation of the reductive elimination products, the cis-alkyl-silyl complexes bearing beta-hydrogens undergo a rapid repetition of the beta-hydrogen elimination and insertion processes, as confirmed by a deuterium-labeling experiment using cis-Pt(CH2CD3)(SiPh3)(PMe2Ph)(2). The alkylsilane formation from the cis isomers proceeds via two reaction paths. One is the direct C-Si reductive elimination. On the other path, the cis-PtR(SiPh3)(PMe2Ph)(2) complexes are initially isomerized to the corresponding cis-PtPh(SiRPh2)(PMe2Ph)(2) complexes by the exchange of the Pt-R group with the Si-Ph group, and the resulting phenyl-silyl complexes reductively eliminate alkylsilanes. The methyl-silyl complex decomposes exclusively by the former path, while the other alkyl-silyl complexes (R = Et, Pr, Bu) follow mainly the latter path. Preparation and thermolysis reaction of the related cis-PtEt(GePh3)(PMe2Ph)(2) are also reported.

  DOI：

  10.1021/om000012t

文献信息

• Mechanisms of Thermal Decomposition of<i>trans</i>- and<i>cis</i>-Dialkylbis(tertiary phosphine)palladium(II). Reductive Elimination and<i>trans</i>to<i>cis</i>Isomerization
  作者：Fumiyuki Ozawa、Takashi Ito、Yoshiyuki Nakamura、Akio Yamamoto

  DOI：10.1246/bcsj.54.1868

  日期：1981.6

  mechanism for the trans to cis isomerization. Evidence to support the mechanism has been obtained by experiments using LiCD3. Thermolysis of cis-PdR2L2 has been demonstrated to proceed through a unimolecular process initiated by a rate-determining dissociation of L to produce a three-coordinate “cis-PdR2L” which reductively eliminates the R groups. Addition of free ligand to the system containing cis-PdMe2L2

  制备了一系列具有不同碱度和体积的叔膦配体（L）的反式和顺式二烷基钯（II）配合物，并研究了它们在溶液中的热解和异构化机理。通过使用烷基锂对顺式二烷基异构体选择性形成的原因的检查揭示了一种新型的由烷基锂促进的反式到顺式异构化。提出了涉及形成钯酸三烷基酯中间体的过程作为反式异构化为顺式异构化的机制。已经通过使用 LiCD3 的实验获得了支持该机制的证据。已证明顺式 PdR2L2 的热解是通过单分子过程进行的，该过程由 L 的决定速率解离引发，以产生三配位的“顺式 PdR2L”，该过程还原性地消除了 R 基团。
• Preparation and characterization of 1,2-dialkyl compounds of dimolybdenum and ditungsten of formula M2R2(NMe2)4 (M.tplbond.M)
  作者：M. H. Chisholm、D. A. Haitko、K. Folting、J. C. Huffman

  DOI：10.1021/ja00404a012

  日期：1981.7

  Abstract : 1,2-M2Cl2 (NMe2)4 compounds, where M = Mo and W, and alkyllithium reagents react in hydrocarbon solvents to give 1,2-M2R2 (NMe2)4 compounds (M-triple bond M), where R = CH2CH3, -Ch2CD3, -CD2CH3, -CH2CH2CH2CH3, -CH(CH3)2, -CH-(CH3)(C2H5), -CH2C(CH3)3, -CH2Si(CH3)3 and -C(CH3)3. These new compounds have been characterized by a combination of physicochemical studies, which include elemental

  摘要: 1,2-M2Cl2 (NMe2)4 化合物，其中 M = Mo 和 W，与烷基锂试剂在烃类溶剂中反应生成 1,2-M2R2 (NMe2)4 化合物（M-三键 M），其中 R = CH2 、-Ch2CD3、-CD2 、-CH2CH2CH2 、-CH(CH3)2、-CH-( )(C2H5)、-CH2C( )3、-CH2Si( )3和-C( )3。这些新化合物的特征是结合了物理化学研究，包括元素分析、质谱、红外光谱和核磁共振光谱。R = CH2 和 -CH( )2 的钼化合物已通过单晶 X 射线衍射研究进行了检查。表征数据确定所有化合物都具有交错的类乙烷 M2N4C2 核。在溶液中，核磁共振研究揭示了反旋转异构体和 gauche 旋转异构体的混合物的存在：随着烷基的体积增加，gauche rotamer 越来越受到青睐。在结晶状态下，已经通过 X 射线研究充分表征了
• Mechanisms of thermal decomposition of diethylbis(triethylphosphine)platinum(II)
  作者：Thomas J. McCarthy、Ralph G. Nuzzo、George M. Whitesides

  DOI：10.1021/ja00402a025

  日期：1981.6
• Azam, Kazi A.; Brown, Michael P.; Cooper, Susan J., Organometallics, 1982, vol. 1, # 9, p. 1183 - 1188
  作者：Azam, Kazi A.、Brown, Michael P.、Cooper, Susan J.、Puddephatt, Richard J.

  DOI：——

  日期：——