methyl 4-{5-[4-(4-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2-fluorophenyl)piperazin-1-yl]-5-oxopent-1-ynyl}-L-phenylalaninate | 1025993-43-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: methyl 4-{5-[4-(4-{(5S)-5-[(acetylamino)methyl]-2-oxo-1,3-oxazolidin-3-yl}-2-fluorophenyl)piperazin-1-yl]-5-oxopent-1-ynyl}-L-phenylalaninate
• 英文别名: methyl (2S)-3-[4-[5-[4-[4-[(5S)-5-(acetamidomethyl)-2-oxo-1,3-oxazolidin-3-yl]-2-fluorophenyl]piperazin-1-yl]-5-oxopent-1-ynyl]phenyl]-2-aminopropanoate
• CAS: 1025993-43-4
• 化学式: C₃₁H₃₆FN₅O₆
• 分子量: 593.655
• InChiKey: WFXLNNGOTSNSDL-BDYUSTAISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  43
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  135
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
  申请人：——

  公开号：US20040204463A1

  公开（公告）日：2004-10-14

  The present invention provides antibacterial agents having the formula I described herein.

  本发明提供了具有以下式I的抗菌剂。
• EP1615917A1
  申请人：——

  公开号：EP1615917A1

  公开（公告）日：2006-01-18
• [EN] N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES DERIVATIVES WITH ANTIBACTERIAL ACTIVITY<br/>[FR] DERIVES DE N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDE A ACTIVITE ANTIBACTERIENNE
  申请人：UPJOHN CO

  公开号：WO2004087697A1

  公开（公告）日：2004-10-14

  The present invention provides antibacterial agents having the Formula (I) described herein or pharmaceutically acceptable salts thereof wherein: A is a structure I, ii, iii, or iv; Bis, W is-N(H)C(=X)-R1, Het, or -Y-HET, in which the Het or -Y-HET is optionally substituted with =S or =O.