6-{3-Methoxy-4-[2-oxo-2-(4-phenylpiperazine-1-yl)ethoxy]phenyl}-1,3-dimethyl-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione | 480992-80-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 6-{3-Methoxy-4-[2-oxo-2-(4-phenylpiperazine-1-yl)ethoxy]phenyl}-1,3-dimethyl-1,5-dihydropyrrolo[3,2-d]pyrimidine-2,4-dione
• 英文别名: 6-[3-methoxy-4-[2-oxo-2-(4-phenylpiperazin-1-yl)ethoxy]phenyl]-1,3-dimethyl-5H-pyrrolo[3,2-d]pyrimidine-2,4-dione
• CAS: 480992-80-1
• 化学式: C₂₇H₂₉N₅O₅
• 分子量: 503.558
• InChiKey: RYWZUEMEXXUQOG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  37
• 可旋转键数：
  6
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  98.4
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• 6-PHENYLDIHYDROPYRROLOPYRIMIDINEDIONE DERIVATIVES
  申请人：Almirall Prodesfarma, S.A.

  公开号：EP1409489A1

  公开（公告）日：2004-04-21
• [EN] 6-PHENYLDIHYDROPYRROLOPYRIMIDINEDIONE DERIVATIVES<br/>[FR] DERIVES DE 6-PHENYLDIHYDROPYRROLOPYRIMIDINEDIONE
  申请人：ALMIRALL PRODESFARMA SA

  公开号：WO2003000694A1

  公开（公告）日：2003-01-03

  6-phenylpyrrolopyrimidinedione derivatives of the formula (I), and pharmaceutically acceptable salts thereof, wherein R?1,R2,R3,R4 and R5¿ are organic residues, L¿1? is a spacer group and R?6¿ is C(O)NR10R11, -S(O)¿2?NR?10R11,-ON=CR 12R13¿, or a heterocyclyl, arylor heteroaryl group, where R?10, R11, R12 and R13¿ are organic residues, have therapeutic potential as A2 adenosine receptor inhibitors.