4-(4'-hydroxycyclohexyl)-2,2,6,6-tetramethylpiperidine | 54118-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 4-(4'-hydroxycyclohexyl)-2,2,6,6-tetramethylpiperidine
• 英文别名: 4-(2,2,6,6-tetramethylpiperidin-4-yl)cyclohexan-1-ol
• CAS: 54118-95-5
• 化学式: C₁₅H₂₉NO
• 分子量: 239.401
• InChiKey: FGGXTQDATCWSFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-(4'-hydroxycyclohexyl)-2,2,6,6-tetramethylpiperidine 、 对甲苯异氰酸酯 生成 4-(4'-N-p-Tolylcarbamoyloxy-cyclohexyl)2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  4-(4'-Hydroxycyclohexyl)-2,2,6,6-tetramethyl piperidines

  摘要：

  具有以下化学式的化合物：- ##SPC1##及其盐，其中R.sub.1、R.sub.2、R.sub.3和R.sub.4相同或不同，每个都是氢、具有1至9个碳原子的烷基残基、具有5至14个碳原子的环烷基残基或具有7至14个碳原子的环烷基烷基残基，Y是氢、0度、具有1至4个碳原子的烷基残基或具有7至12个碳原子的芳基残基，Z是氢、具有1至20个碳原子的未取代或取代的烷基残基、具有2至20个碳原子的烯烃或炔烃残基、具有5至12个碳原子的环烷基残基、具有7至12个碳原子的芳基残基、具有6至12个碳原子的芳基残基或具有以下化学式的基团：其中Z.sub.1具有与前述Z相同的意义，或Z.sub.1是一个基团--NR.sub.5 R.sub.6，其中R.sub.5是氢或具有1至4个碳原子的烷基残基，R.sub.6是氢、具有1至20个碳原子的烷基基团、具有5至12个碳原子的环烷基基团、具有7至12个碳原子的芳基残基或具有6至12个碳原子的芳基残基，具有光稳定活性。

  公开号：

  US03954779A1
• 作为产物：
  描述：

  4-(2,2,6,6-tetramethyl-piperidin-4-yl)-phenol 在 钌 作用下， 以 乙醇 、 氯仿 、 水 为溶剂， 生成 4-(4'-hydroxycyclohexyl)-2,2,6,6-tetramethylpiperidine
  参考文献：
  名称：

  4-(4'-Hydroxycyclohexyl)-2,2,6,6-tetramethyl piperidines

  摘要：

  具有以下化学式的化合物：- ##SPC1##及其盐，其中R.sub.1、R.sub.2、R.sub.3和R.sub.4相同或不同，每个都是氢、具有1至9个碳原子的烷基残基、具有5至14个碳原子的环烷基残基或具有7至14个碳原子的环烷基烷基残基，Y是氢、0度、具有1至4个碳原子的烷基残基或具有7至12个碳原子的芳基残基，Z是氢、具有1至20个碳原子的未取代或取代的烷基残基、具有2至20个碳原子的烯烃或炔烃残基、具有5至12个碳原子的环烷基残基、具有7至12个碳原子的芳基残基、具有6至12个碳原子的芳基残基或具有以下化学式的基团：其中Z.sub.1具有与前述Z相同的意义，或Z.sub.1是一个基团--NR.sub.5 R.sub.6，其中R.sub.5是氢或具有1至4个碳原子的烷基残基，R.sub.6是氢、具有1至20个碳原子的烷基基团、具有5至12个碳原子的环烷基基团、具有7至12个碳原子的芳基残基或具有6至12个碳原子的芳基残基，具有光稳定活性。

  公开号：

  US03954779A1

文献信息

• Liquid crystal mixture
  申请人：Clariant International Ltd.

  公开号：EP1184442A1

  公开（公告）日：2002-03-06

  Liquid crystal mixture containing one or several compounds of formula (I) wherein R1: is H or a linear or branched alkyl group of 1 to 20 C atoms, wherein optionally one -CH2- group being replaced by cyclohexylen-1,4-diyl, or one or two -CH2- groups optionally being replaced by -O-, if non-adjacent to N, or by -C(=O)-, -Si(CH3)2-; or one or more H optionally being replaced by F or CH3 R2:stands for a) H or F b) a linear or branched alkyl group of 1 to 20 C atoms, wherein one or two -CH2- groups optionally being replaced by -O-, -C(=O)O-, -Si(CH3)2-, or one or more H being replaced by F or CH3. c) a radical of formula (II) R3, R4, R5, R6: are independently from another an alkyl group of 1 to 8 C atoms M1, M2: represent independently a single bond, -OC(=O), -C(=O)O-, -OCH2-, -NH- A: is a) a linear or branched alkyl group of 1 to 20 C atoms, optionally, if non-adjacent to M1/2, one or two non-adjacent -CH2- groups may be replaced by -O- b) the group -C(=Y)- wherein Y is CH-Z with Z being phenylen-1,4-diyl, optionally substituted by one to three halogenatoms, alkyl or alkyloxy groups of 1 to 4 C atoms, with the proviso that M1 and M2 are -C(=O)O- and -OC(=O)-, c) the group -CHY wherein Y is CH2-Z with Z being phenylen-1,4-diyl, optionally substituted by one to three halogenatoms, alkyl or alkyloxy groups of 1 to 4 C atoms, with the proviso that M1 and M2 are -C(=O)O- and -OC(=O)-, d) a group wherein p, q are 0, 1 or 2, the sum of p + q being ≥ 1; M3 is a single bond or -OC(=O)-, -C(=O)O-, -OCH2-, -CH2O-, -C≡C-, -CH2CH2-, -CH2CH2CH2CH2 the radicals represent independently from another phenylen-1,4-diyl, optionally substitued by one, two or three F, or cyclohexan-1,4-diyl, optionally substituted by one CN, CH3 or F, or pyrimidin-2,5-diyl, optionally substituted by one F, or pyridine-2,5-diyl, optionally substituted by one F, or naphthalin-2,6-diyl, optionally substituted by one, two or three F, or (1,3,4)thiadiazol-2,5-diyl, thiophen-2,4-diyl, thiophen-2,5-diyl, (1,3)dioxan-2,5-diyl, piperidin-1,4-diyl, or piperazin-1,4-diyl X is H, OH, a linear or branched alkyl or alkyloxy group of 1 to 20 C atoms, wherein one or two -CH2- groups can be replaced by -O-, -C(=O)O-, -Si(CH3)2-, optionally one or more H being replaced by F or CH3 m: is 0 or 1 X and M1-(A)m-M2-R2 together can constitute a) a ring of 4 to 16 members, optionally substituted by an alkyl radical of 1 to 15 C atoms b) a combination of two either directly linked or spiro-linked rings of independently from another 4 to 16 members, optionally substituted by an alkyl radical of 1 to 15 C atoms in either of the three variants the rings independently from another being carbocycles or carbocycles containing B, N, O or S heteroatoms.

  含有一个或多个式(I)中的化合物的液晶混合物，其中R1：为H或1至20个C原子的线性或支链烷基，其中可选地一个-CH2-基被环己基-1,4-二基取代，或者一个或两个- -基可选地被-O-取代，如果非相邻于N，则为-C（=O）-，-Si（CH3）2-;或一个或多个H可选地被F或 取代。R2：代表a）H或Fb）1至20个C原子的线性或支链烷基，其中一个或两个- -基可选地被-O-，-C（=O）O-，-Si（ ）2-取代，或一个或多个H被F或 取代。c）式（II）中的基团R3，R4，R5，R6：分别独立地是1至8个C原子的烷基M1，M2：分别独立地表示单键，-OC（=O），-C（=O）O-，-O -，-NH-A：a）是1至20个C原子的线性或支链烷基，如果非相邻于M1/2，则可选地用- O-替换一个或两个非相邻的- -基b）-C（=Y）-，其中Y为CH-Z，Z为苯基-1,4-二基，可选地被1至4个C原子的卤素原子，烷基或烷氧基取代，具有M1和M2为-C（=O）O-和-OC（=O）-的条件c）-CHY，其中Y为 -Z，Z为苯基-1,4-二基，可选地被1至4个C原子的卤素原子，烷基或烷氧基取代，具有M1和M2为-C（=O）O-和-OC（=O）-的条件d）一组，其中p，q为0,1或2，p + q的总和≥1；M3是单键或-OC（=O）-，-C（=O）O-，-O -，- O-，-C≡C-，- -，- -，基团独立地代表苯基-1,4-二基，可选地取代一个，两个或三个F，或环己基-1,4-二基，可选地取代一个CN， 或F，或嘧啶-2,5-二基，可选地取代一个F，或吡啶-2,5-二基，可选地取代一个F，或萘-2,6-二基，可选地取代一个，两个或三个F，或（1,3,4）噻二唑-2,5-二基，噻吩-2,4-二基，噻吩-2,5-二基，（1,3）二氧杂环戊烷-2,5-二基，哌啶-1,4-二基或哌嗪-1,4-二基X为H，OH，1至20个C原子的线性或支链烷基或烷氧基，其中一个或两个- -基可被-O-，-C（=O）O-，-Si（ ）2-取代，可选地一个或多个H被F或 取代m：为0或1X和M1-（A）m-M2-R2一起可以构成a）具有4至16个成员的环，可选地被1至15个C原子的烷基取代b）两个直接连接或螺旋连接的环的组合，独立地具有4至16个成员，可选地被1至15个C原子的烷基取代，在这三种变体中，环独立地为碳环或含有B，N，O或S杂原子的碳环。
• 2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines and synthetic polymer compositions stabilized thereby
  申请人：ADEKA ARGUS CHEMICAL CO., Ltd.

  公开号：EP0022997A1

  公开（公告）日：1981-01-28

  2,2,6,6-Tetramethyl-4-piperidyl carboxylic acid esters and amides of mono and poly alcohols, phenols and amines are provided, useful as stabilizers for organic polymeric materials, and having the general formula: wherein: R1, R2 and R3 are selected from the group consisting of hydrogen and alkyl having from one to about eighteen carbon atoms; X is oxygen or imino >NH; m is zero, 1 or 2; n is zero, 1 or 2; m + n is 1 or 2; p is zero or 1; q is 1 to 6; is linked to carbon in place of one R2 or R, group; and is selected from the group consisting of: (a) OR5 where R5 is alkyl, aryl or cycloalkyl having one to twenty-four carbon atoms and hydroxy-, carboxy- and oxy-substituted such groups having from one to five OH or O groups; and 2,2,6,6-tetramethyl-4-piperidyl; (b) OReO where Re is alkylene, arylene or cycloalkylene having one to twenty-four carbon atoms and hydroxy-substituted such groups having one to four OH groups; Re alkylene, aryiene or cycloalkylene can include oxyether -0- and thioether -S- linking groups attached to alkylene, arylene or cycloalkylene groups as in polyoxyalkylene and polythioalkylene groups and polyoxyalkylene arylene groups having from one to about five oxy or thio groups and from two to about six alkylene groups having (c) from two to about six carbon atoms; where R6 is alkylene, arylene or cycloalkylene having one to twenty-four carbon atoms and hydroxy-substituted such groups having one to four OH groups; R6 alkylene, arylene or cycloalkylene can include oxyether -O- and thioether -S- linking groups attached to alkylene, arylene or cycloalkylene groups as in polyoxyalkylene and polythioalkylene groups and polyoxyalkylene arylene groups having from one to about five oxy or thio groups and from two to about six alkylene groups having from two to about six carbon atoms; R7 is alkyl, aryl or cycloalkyl having one to twenty-four carbon atoms and hydroxy-substituted such groups having from one to five OH groups; (d) where R5 is alkyl, aryl or cycloalkyl having one to twenty-four carbon atoms and amino-substituted such groups having (e) from one to five amino groups; where R6 is alkylene, arylene or cycloalkylene having one to twenty-four carbon atoms and amino-substituted such groups having one to four amino groups; R7 is alkyl, aryl or cycloalkyl having one to twenty-four carbon atoms and amino-substituted such groups having one to five amino groups; (f)-NHNH2; -NHNH-; -NHNHCOCONHNH2; NHNHCOR7; -NHNHCOR6CONHNH2; -NHNHCOR6CONHNH-; -NHNHCOCONHNH-,; -NHR6NH2-; -NHR6NH-; where Rs is alkylene, arylene or cycloalkylene having one to twenty-four carbon atoms and amino-substituted such groups having one to four amino groups; and such groups including oxyether and thioether linking groups as in (b) above, and R7 is as in (c) above.

  本发明提供了 2,2,6,6-四甲基-4-哌啶基羧酸酯和一元醇和多元醇、酚和胺的酰胺，可用作有机聚合物材料的稳定剂，其通式为 其中 R1、R2 和 R3 选自氢和具有 1 至约 18 个碳原子的烷基组成的组； X 是氧或亚胺 >NH； m 为零、1 或 2 n 为零、1 或 2 m + n 为 1 或 2； p 为 0 或 1 q 为 1 至 6； 与碳相连，代替一个 R2 或 R, 基团；以及 选自以下组成的组 (a) OR5，其中 R5 是具有 1 至 24 个碳原子的烷基、芳基或环烷基，以及具有 1 至 5 个 OH 或 O 基团的羟基、羧基和氧基取代的此类基团；以及 2,2,6,6-四甲基-4-哌啶基； (b) OReO 其中 Re 为具有 1 至 24 个碳原子的亚烷基、芳基或环烷基，以及具有 1 至 4 个 OH 基团的羟基取代的此类基团；Re亚烷基、芳基或环烷基可包括连接到亚烷基、芳基或环烷基上的氧醚 -0- 和硫醚 -S- 连接基团，如聚氧亚烷基、聚硫亚烷基和聚氧亚烷基芳基中的氧醚 -0- 和硫醚 -S- 连接基团，这些基团具有 1 至 5 个氧基或硫代基团和 2 至 6 个亚烷基，这些亚烷基具有 (c) R6是具有一至二十四个碳原子的亚烷基、芳基或环烷基，以及具有一至四个羟基的羟基取代的亚烷基、芳基或环烷基；R6 亚烷基、亚芳基或环烷基可包括连接到亚烷基、亚芳基或环烷基上的氧醚 -O- 和硫醚 -S- 连接基团，如聚氧亚烷基和聚硫亚烷基以及聚氧亚烷基亚芳基中的氧醚 -O- 和硫醚 -S- 连接基团，这些亚烷基、亚芳基或环烷基具有一至约五个氧或硫基和二至约六个亚烷基，这些亚烷基具有二至约六个碳原子；R7 是具有一至二十四个碳原子的烷基、芳基或环烷基，以及具有一至五个羟基的羟基取代的此类基团； (d) 其中 R5 是具有一至二十四个碳原子的烷基、芳基或环烷基和具有 (e) R6 是具有 1 至 24 个碳原子的亚烷基、芳基或环烷基，以及具有 1 至 4 个氨基的氨基取代的此类基团；(f)-NHNH2; -NHNH-; -NHNHCOCONHNH2; NHNHCOR7; -NHNHCOR6CONHNH2; -NHNHCOR6CONHNH-; -NHNHCOCONHNH-,; -NHR6NH2-;-NHR6NH-； 其中 Rs 是具有一至二十四个碳原子的亚烷基、芳烯基或环烷基，以及具有一至四个氨基的氨基取代的此类基团；此类基团包括如上文(b)所述的氧醚和硫醚连接基团，R7 如上文(c)所述。
• 2,2,6,6-Tetraalkyl-4-piperidyl alcohol esters of tetradecylene polycarboxylic acids as light stabilizers for synthetic polymers and stabilized compositions
  申请人：ADEKA ARGUS CHEMICAL CO., Ltd.

  公开号：EP0023330A1

  公开（公告）日：1981-02-04

  2,2,6,6-Tetraalkyl -4-piperidyl alcohol esters of tet- adecylene polycarboxylic acids are provided, useful as light stabilizers for organic polymeric materials, and having the general formula: in which: R is selected from the group consisting of wherein: R5 and R6 are each hydrogen or lower alkyl or hydroxyalkyl having from one to about six carbon atoms; R7 is lower alkyl having from one to about six carbon atoms; R1 R1, R, and R, are selected from the group consisting of hydrogen and methyl; X and X3 are selected from the group consisting of hydrogen and COOR; X2 and X4 are selected from the group consisting of COOR and 30 wherein: R3, R9 and R10 are selected from the group consisting of hydrogen, hydroxy, alkyl, and alkoxy having from one to about eighteen carbon atoms.

  本发明提供了 2,2,6,6-四烷基-4-哌啶醇酯，可用作有机聚合物材料的光稳定剂，其通式如下： 其中 R 选自以下组成的组 其中 R5 和 R6 分别是氢或具有 1 至约 6 个碳原子的低级烷基或羟基烷基； R7 是具有 1 至约 6 个碳原子的低级烷基； R1 R1、R 和 R 选自氢和甲基组成的组； X 和 X3 选自由氢和 COOR 组成的组； X2 和 X4 选自由 COOR 和 COOR 组成的组。 30 其中 R3、R9 和 R10 选自氢、羟基、烷基和具有 1 至约 18 个碳原子的烷氧基组成的组。
• LIQUID CRYSTAL MIXTURE
  申请人：CLARIANT INTERNATIONAL LTD.

  公开号：EP1319054A1

  公开（公告）日：2003-06-18
• US4210577A
  申请人：——

  公开号：US4210577A

  公开（公告）日：1980-07-01