1-{Bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-2-[tris-(2-{bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-ethyl)-silanyl]-ethane | 199983-94-3

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: 1-{Bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-2-[tris-(2-{bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-ethyl)-silanyl]-ethane
• 英文别名: Tetrakis[2-[bis[2-[chloromethyl(dimethyl)silyl]ethyl]-methylsilyl]ethyl]silane
• CAS: 199983-94-3
• 化学式: C₅₂H₁₂₄Cl₈Si₁₃
• 分子量: 1398.29
• InChiKey: PAWZGUMDGQTCPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  23.64
• 重原子数：
  73
• 可旋转键数：
  44
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2-甲胺乙硫醇盐酸盐 、 1-{Bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-2-[tris-(2-{bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-ethyl)-silanyl]-ethane 在 sodium hydroxide 作用下， 以 水 、 异丙醇 为溶剂， 反应 11.0h， 以92%的产率得到2-[[2-[2-[2-(dimethylamino)ethylsulfanylmethyl-dimethylsilyl]ethyl-methyl-[2-[tris[2-[bis[2-[2-(dimethylamino)ethylsulfanylmethyl-dimethylsilyl]ethyl]-methylsilyl]ethyl]silyl]ethyl]silyl]ethyl-dimethylsilyl]methylsulfanyl]-N,N-dimethylethanamine
  参考文献：
  名称：

  Synthesis of Water-Soluble Carbosilane Dendrimers

  摘要：

  Nucleophilic reactions between mercapto-substituted amphiphiles and carbosilane dendrimers bearing (chloromethyl)silyl groups on their terminal branches gave, in high yields, amphiphilic dendrimers with hydrophobic carbosilane cores and alcohol, dimethylamino, or sodium sulfonate amphiphilic groups at the periphery. The negatively charged, sulfonate-terminated dendrimers were soluble in water, as were positively charged poly(ammonium) salts prepared from the dimethylamino-terminated derivatives. These new amphiphilic dendrimers were characterized by spectroscopic and mass spectrometric techniques. Preliminary studies of the aqueous solution behavior of the second generation, sulfonate-terminated dendrimer demonstrated its ability to enhance the solubility of lipophilic allyl-substituted benzene derivatives, a characteristic property of micelles.

  DOI：

  10.1021/ja971865o
• 作为产物：
  描述：

  氯甲基(二甲基)硅烷 、 [Silanetetrayltetra(ethane-2,1-diyl)]tetrakis[diethenyl(methyl)silane] 在 platinum divinyltetramethyldisiloxane 作用下， 以 四氢呋喃 为溶剂， 反应 19.0h， 以52%的产率得到1-{Bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-2-[tris-(2-{bis-[2-(chloromethyl-dimethyl-silanyl)-ethyl]-methyl-silanyl}-ethyl)-silanyl]-ethane
  参考文献：
  名称：

  Synthesis of Water-Soluble Carbosilane Dendrimers

  摘要：

  Nucleophilic reactions between mercapto-substituted amphiphiles and carbosilane dendrimers bearing (chloromethyl)silyl groups on their terminal branches gave, in high yields, amphiphilic dendrimers with hydrophobic carbosilane cores and alcohol, dimethylamino, or sodium sulfonate amphiphilic groups at the periphery. The negatively charged, sulfonate-terminated dendrimers were soluble in water, as were positively charged poly(ammonium) salts prepared from the dimethylamino-terminated derivatives. These new amphiphilic dendrimers were characterized by spectroscopic and mass spectrometric techniques. Preliminary studies of the aqueous solution behavior of the second generation, sulfonate-terminated dendrimer demonstrated its ability to enhance the solubility of lipophilic allyl-substituted benzene derivatives, a characteristic property of micelles.

  DOI：

  10.1021/ja971865o