1-(1,4,7,10,13-pentaoxacyclopentadec-2-yl)-N,N-bis[(5-thiophen-2-ylthiophen-2-yl)methyl]methanamine | 1082752-85-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 双噻吩和低聚噻吩
• 英文名称: 1-(1,4,7,10,13-pentaoxacyclopentadec-2-yl)-N,N-bis[(5-thiophen-2-ylthiophen-2-yl)methyl]methanamine
• CAS: 1082752-85-9
• 化学式: C₂₉H₃₅NO₅S₄
• 分子量: 605.865
• InChiKey: LPLJKKKQBWXHMT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  39
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  162
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  2,2-联噻吩-5-乙醛 、 2-氨基甲基-15-冠-5 在 三乙酰氧基硼氢化钠 作用下， 以 1,2-二氯乙烷 为溶剂， 以32%的产率得到1-(1,4,7,10,13-pentaoxacyclopentadec-2-yl)-N,N-bis[(5-thiophen-2-ylthiophen-2-yl)methyl]methanamine
  参考文献：
  名称：

  Synthesis and evaluation of bipendant-armed (oligo)thiophene crown ether derivatives as new chemical sensors

  摘要：

  Three new (oligo)thiophene bipendant-armed ligands 2a-c, derived from 2-(aminomethyl)-15-crown-5, have been synthesized and characterized. Compounds 2a-c were prepared by reductive amination of the corresponding macrocycle with formyl thiophene derivatives la-c in the presence of NaBH(ClAc) in fair, to good yields. The photophysical properties of ligands 2a-c were Studied and they were also evaluated as chemosensors in the presence of Na(I), Ag(I), Pd(II) and Hg(II) cations in acetonitrile Solution. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.09.036