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7-(4-aminophenethyl)-N-(4-(4-ethylpiperazin-1-yl)phenyl)thieno[3,2-d]pyrimidine-4-amine | 1318128-73-2

中文名称
——
中文别名
——
英文名称
7-(4-aminophenethyl)-N-(4-(4-ethylpiperazin-1-yl)phenyl)thieno[3,2-d]pyrimidine-4-amine
英文别名
7-[2-(4-aminophenyl)ethyl]-N-[4-(4-ethylpiperazin-1-yl)phenyl]thieno[3,2-d]pyrimidin-4-amine
7-(4-aminophenethyl)-N-(4-(4-ethylpiperazin-1-yl)phenyl)thieno[3,2-d]pyrimidine-4-amine化学式
CAS
1318128-73-2
化学式
C26H30N6S
mdl
——
分子量
458.63
InChiKey
BLEFQUXREXWQGL-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    5
  • 重原子数:
    33
  • 可旋转键数:
    7
  • 环数:
    5.0
  • sp3杂化的碳原子比例:
    0.31
  • 拓扑面积:
    98.6
  • 氢给体数:
    2
  • 氢受体数:
    7

文献信息

  • BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE
    申请人:Jung Seung Hyun
    公开号:US20120302567A1
    公开(公告)日:2012-11-29
    The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.
    本发明涉及一种新颖的双环杂环芳基衍生物,其药用盐,合物和溶剂合物,具有改进的蛋白激酶抑制活性,并且包括作为活性成分的药物组合物,用于预防或治疗异常细胞生长紊乱。
  • Bicyclic heteroaryl derivatives having inhibitory activity for protein kinase
    申请人:Jung Seung Hyun
    公开号:US10112954B2
    公开(公告)日:2018-10-30
    The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.
    本发明涉及一种新型双环杂芳基衍生物、其药学上可接受的盐、其合物和其溶液,该衍生物对蛋白激酶的抑制活性有所提高,本发明还涉及一种用于预防或治疗异常细胞生长紊乱的药物组合物,该药物组合物的有效成分包括双环杂芳基衍生物、其药学上可接受的盐、其合物和其溶液。
  • THIENOPYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE
    申请人:Hanmi Pharm. Co., Ltd.
    公开号:EP3141552B1
    公开(公告)日:2019-04-17
  • [EN] BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE<br/>[FR] DÉRIVÉS HÉTÉROARYLE BICYCLIQUE AYANT UNE ACTIVITÉ INHIBITRICE DE PROTÉINE KINASE
    申请人:HANMI PHARM IND CO LTD
    公开号:WO2011093672A2
    公开(公告)日:2011-08-04
    The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.
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