1-(丁-2-烯基)哌啶 | 699-14-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 1-(丁-2-烯基)哌啶
• 英文名称: N-crotonyl-piperidine
• 英文别名: 1-Piperidyl-2-butene；1-but-2-enylpiperidine
• CAS: 699-14-9
• 化学式: C₉H₁₇N
• 分子量: 139.241
• InChiKey: XQOHGUZOLKLXLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(丁-2-烯基)哌啶 、 2-(三甲基硅)苯基三氟甲烷磺酸盐 在 cerium monofluoride 作用下， 以 乙二醇二甲醚 为溶剂， 反应 48.0h， 以31%的产率得到1-[2-(1-methyl-allyl)-phenyl]-piperidine
  参考文献：
  名称：

  Benzyne Aza-Claisen 反应

  摘要：

  将芳炔加入叔烯丙胺中得到aza-Claisen 重排的邻烯丙胺产物。芳炔同时为重排和季铵化事件提供 π 分量，从而降低 sigmatropic 位移的活化能。该反应用于合成中环苯并环胺（见方案）。

  DOI：

  10.1002/anie.200901410

文献信息

• Method for Producing Modified Conjugated Diene-Based Polymer, Modified Conjugated Diene-Based Polymer, Modified Conjugated Diene-Based Polymer Composition, Rubber Composition and Tire
  申请人：Yamada Chigusa

  公开号：US20140213721A1

  公开（公告）日：2014-07-31

  A method for producing a modified conjugated diene-based polymer including a polymerization step of obtaining a conjugated diene-based polymer having an active end by use of a polymerization initiator containing a compound having at least one nitrogen atom in a molecule and an organic lithium compound; and a modification step of reacting a modifier represented by the following chemical formula (6) with the active end of the conjugated diene-based polymer: wherein R 4 to R 7 each independently represent an alkyl group having 1 to 20 carbon atoms or an aryl group having 6 to 20 carbon atoms; R 8 represents an alkylene group having 3 to 10 carbon atoms; R 9 represents an alkylene group having 1 to 20 carbon atoms; m is an integer of 1 or 2; and n is an integer of 2 or 3.

  一种生产改性共轭二烯基聚合物的方法，包括以下步骤： 1. 通过使用含有至少一个氮原子的化合物和有机锂化合物的聚合引发剂，进行聚合反应步骤，以获得具有活性端的共轭二烯基聚合物。 2. 使用以下化学式（6）表示的改性剂与共轭二烯基聚合物的活性端反应，进行改性步骤： 其中，R4至R7各自独立地表示具有1至20个碳原子的烷基或具有6至20个碳原子的芳基；R8表示具有3至10个碳原子的烷基；R9表示具有1至20个碳原子的烷基；m为1或2的整数；n为2或3的整数。
• Pharmaceutical composition for treating a condition exhibiting pain, fever, and inflammation comprising 2-(substituted piperidinomethyl) propane- and propene nitriles
  申请人：Merck & Co., Inc.

  公开号：EP0024356A1

  公开（公告）日：1981-03-04

  Pharmaceutical compositions for treating pain, fever, and inflammation, wherein the active ingredient comprises a compound of the formula: or wherein A and R1 represent various substituents.

  用于治疗疼痛、发烧和炎症的药物组合物，其中活性成分包括式中的化合物： 或 其中 A 和 R1 代表各种取代基。
• 2-Methyl-4, 4A-dihydro-3H-carbazolium salts and dyes derived therefrom
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0561686A1

  公开（公告）日：1993-09-22

  2-Methyl-4,4a-dihydro-3H-carbazolium salts that are useful as dye precursors and dyes derived from those precursors are disclosed. The salts are described by the formula wherein R¹ represents an alkyl, aryl, sulfoalkyl, carboxyalkyl, sulfatoalkyl, alkoxyalkyl, acyloxyalkyl, dialkylaminoalkylene, cycloaminoalkylene, acyl, or alkenyl group having from 1 to 18 carbon atoms; R² represents an alkyl group having up to 18 carbon atoms; R³represents hydrogen or an alkyl group having from 1 to 18 carbon atoms; R⁴ represents hydrogen or an alkyl group having from 1 to 18 carbon atoms; R⁵ represents hydrogen, nitro, carboxyl, sulfo, hydroxy, halogen, phospho, or an alkoxy, thioalkoxy, oxyalkyl, acyl, alkyl, aryl, or amino group having up to 18 carbon atoms; wherein any two groups R⁵, or R⁴ and a group R⁵, or R¹ and R⁴ may together form a substituted or unsubstituted aryl, heteroaryl, aliphatic, or heteroaliphatic ring; X represents an anion; and a and b represent positive integers such that a equals b. The salts have a partially saturated ring system that rigidifies the chromophore in the precursor and in dyes derived from it. The rigidified chromophores have narrowed absorption bands relative to corresponding non-rigid chromophores. Dyes prepared from the dye precursors of the invention typically have good solubility in non-polar solvents.

  本发明公开了可用作染料前体的 2-甲基-4,4a-二氢-3H-咔唑盐以及由这些前体衍生的染料。这些盐的结构式如下 其中 R¹ 代表具有 1 至 18 个碳原子的烷基、芳基、磺酰基、羧基、硫代烷基、烷氧基烷基、酰氧基烷基、二烷基氨基烷基、环氨基烷基、酰基或烯基；R² 代表具有多达 18 个碳原子的烷基；R³ 代表氢或具有 1 至 18 个碳原子的烷基；R⁴ 代表氢或具有 1 至 18 个碳原子的烷基；R⁵ 代表氢、硝基、羧基、磺基、羟基、卤素、膦基或具有多达 18 个碳原子的烷氧基、硫代烷氧基、氧代烷基、酰基、烷基、芳基或氨基；其中任意两个基团 R⁵ 或 R⁴ 和一个基团 R⁵ 或 R¹ 和 R⁴ 可共同形成取代或未取代的芳基、杂芳基、脂族或杂脂族环；X 代表阴离子；a 和 b 代表正整数，使得 a 等于 b。 盐类具有部分饱和的环系统，可硬化前体和衍生染料中的发色团。与相应的非刚性发色团相比，刚性发色团的吸收带变窄。由本发明染料前体制备的染料通常在非极性溶剂中具有良好的溶解性。
• MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER COMPOSITION, TIRE, AND METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER
  申请人：Japan Elastomer Co., Ltd.

  公开号：EP3517552A1

  公开（公告）日：2019-07-31

  A modified conjugated diene polymer satisfying the following conditions (I) to (IV): (I) at least two peaks are observed in a molecular weight distribution curve obtained from measurement by gel permeation chromatography (GPC); (II) when a peak of the highest molecular weight is defined as a peak (B), a peak of the largest peak area except for the peak (B) is defined as a peak (T) in the molecular weight distribution curve, a peak molecular weight of the peak (B) is from 500,000 to 2,500,000 and a peak molecular weight of the peak (T) is from 150,000 to 600, 000; (III) an area of the peak (T) is from 30% to 80% and a total value of an area of the peak (B) and the area of the peak (T) is 65% or more when the total area of the molecular weight distribution curve is defined as 100%; and (IV) a proportion of a modified polymer chain(s) in a region ranging from a low-molecular-weight side to a point of 5% cumulative area is from 60% to 99% in the molecular weight distribution curve.

  满足以下条件(I)至(IV)的改性共轭二烯聚合物： (I) 通过凝胶渗透色谱法（GPC）测量得到的分子量分布曲线中至少有两个峰； (II) 当分子量最高的峰被定义为峰（B）时，分子量分布曲线中除峰（B）外峰面积最大的峰被定义为峰（T），峰（B）的峰分子量为 500,000 至 2,500,000 之间，峰（T）的峰分子量为 150,000 至 600,000 之间； (III) 当分子量分布曲线的总面积定义为 100%时，峰（T）的面积为 30%至 80%，峰 （B）的面积和峰（T）的面积的总值为 65%或以上；以及 (IV) 在分子量分布曲线中，从低分子量侧到累积面积为 5%的点的区域中，改性聚合物 链的比例为 60%至 99%。
• Modified conjugated diene-based polymer and method for producing the same, and modified conjugated diene-based polymer composition
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：US10766972B2

  公开（公告）日：2020-09-08

  The present invention provides a modified conjugated diene-based polymer, wherein the Mooney stress-relaxation rate measured at 110° C. is 0.45 or less, and the modification percentage is 75% by mass or more.

  本发明提供了一种改性共轭二烯基聚合物，其中在 110° C 时测得的门尼应力松弛率为 0.45 或更低，改性百分比为 75% 或更高。