6-O-三苯基甲基-alpha-d-吡喃葡萄糖 | 54325-28-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 中文名称: 6-O-三苯基甲基-alpha-d-吡喃葡萄糖
• 英文名称: 6-O-trityl-α-D-glucose
• 英文别名: O⁶-Trityl-α-D-glucopyranose；(2S,3R,4S,5S,6R)-6-((Trityloxy)methyl)tetrahydro-2H-pyran-2,3,4,5-tetraol；(2S,3R,4S,5S,6R)-6-(trityloxymethyl)oxane-2,3,4,5-tetrol
• CAS: 54325-28-9
• 化学式: C₂₅H₂₆O₆
• 分子量: 422.478
• InChiKey: WMNZCEKHTHLIRQ-SJSRKZJXSA-N

物化性质

• 沸点：
  595.6±50.0 °C(Predicted)
• 密度：
  1.332±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

安全信息

• 海关编码：
  2932999099
• 危险性防范说明：
  P261,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为反应物：
  描述：

  6-O-三苯基甲基-alpha-d-吡喃葡萄糖 在 吡啶 、 溶剂黄146 作用下， 反应 0.5h， 生成 1,2,3,4-tetra-O-acetyl-α-D-glucopyranoside
  参考文献：
  名称：

  Utamura, Toshiko; Kuromatsu, Keiko; Suwa, Kiyoko, Chemical and pharmaceutical bulletin, 1986, vol. 34, p. 2341 - 2353

  摘要：

  DOI：
• 作为产物：
  描述：

  三苯基氯甲烷 、 alpha-甲基葡萄糖甙 在 三乙烯二胺 作用下， 以 二氯甲烷 为溶剂， 生成 6-O-三苯基甲基-alpha-d-吡喃葡萄糖
  参考文献：
  名称：

  Cu 催化的双 C(sp3)–H 官能化乙芳烃形成芳基乙醇胺

  摘要：

  报道了乙芳烃与醇和N-氟苯磺酰亚胺的双 C(sp 3 )–H 官能化。反应分三个阶段进行。(1) 铜催化的乙基芳烃苄基烷氧基化得到 1-(1-烷氧基乙基) 苯。(2) 生成的 1-(1-烷氧基乙基) 苯逐渐转化为乙烯基芳烃。(3) Cu 催化的中间乙烯基芳烃的氨基烷氧基化产生芳基乙醇胺。总的来说，C-N 和 C-O 键被区域选择性地引入到乙基芳烃的同苄基和苄基位置。

  DOI：

  10.1021/acs.joc.3c00583

文献信息

• SHORT SYNTHETIC PATHWAY FOR 1,6:2,3-DIANHYDRO-BETA-D-MANNOPYRANOSE
  申请人：Bouvenot Laurent

  公开号：US20110224446A1

  公开（公告）日：2011-09-15

  The invention relates to a method for preparing 1,6:2,3-dianhydro-β-D-mannopyranose and is characterized in that it includes a step of cyclizing the compound B, where R is an activating agent, in the presence of a base selected from among ammonium hydroxides and mineral bases.

  本发明涉及一种制备1,6:2,3-二去水-β-D-甘露糖苷的方法，其特征在于，它包括在氨水和矿物质碱中选择一种碱的存在下，将化合物B环化的步骤，其中R是一种活性剂。
• Guanidine-Containing Molecular Transporters: Sorbitol-Based Transporters Show High Intracellular Selectivity toward Mitochondria
  作者：Kaustabh K. Maiti、Woo Sirl Lee、Toshihide Takeuchi、Catherine Watkins、Marjan Fretz、Dong-Chan Kim、Shiroh Futaki、Arwyn Jones、Kyong-Tai Kim、Sung-Kee Chung

  DOI：10.1002/anie.200701346

  日期：2007.8.3
• Self-Assembly of β-Glucosidase and <scp>d</scp>-Glucose-Tethering Zeolite Crystals into Fibrous Aggregates
  作者：Goo Soo Lee、Yun-Jo Lee、So Yeun Choi、Yong Soo Park、Kyung Byung Yoon

  DOI：10.1021/ja0028222

  日期：2000.12.1

  beta -Glucosidase and D-glucose-tethering micrometer-sized zeolite crystals self-assemble into thin (2-20 mum) and very long (>1 cm) fibrous aggregates in water. The process proceeds at a faster rate in a buffer solution of pH 4.8 at which the enzymatic activity is highest. The zeolite and enzyme remain intact within the fibrous material. Furthermore, the enzymatic activity of beta -glucosidase is preserved even after they are kept in water for more than 6 months at room temperature. With the zeolite to enzyme weight ratio of 5, all the zeolite crystals are buried within the round fibrils which consist of either a single strand or helical double strands. Upon increasing the ratio to 10, clusters of unburied zeolite crystals appear on the exterior of the fibrils, while narrow flat fibers with smooth surfaces are formed upon decreasing the ratio to 2.5. The process is proposed to initiate by the tight binding between the zeolite-bound D-glucose moieties and beta -glucosidase followed by crystallization of the enzyme over the zeolite-bound enzyme monolayer. This report thus reveals a novel behavior of beta -glucosidase and demonstrates an unprecedented phenomenon that an enzyme and its substrate-tethering inorganic crystals self-assemble into structured aggregates.
• Helferich; Moog; Juenger, Chemische Berichte, 1925, vol. 58, p. 880
  作者：Helferich、Moog、Juenger

  DOI：——

  日期：——
• Procédé de synthèse organique d'oligosaccharides, correspondant à des fragments de muco-polysaccharides naturels, nouveaux oligosaccharides obtenus et leurs applications biologiques
  申请人：D.R.O.P.I.C. (Société Civile)

  公开号：EP0084999B1

  公开（公告）日：1988-04-13