1-isopropylsulfanyl-piperidine | 61076-33-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1-isopropylsulfanyl-piperidine
• 英文别名: 1-(propane-2-sulfenyl)-piperidine；1-(Propan-2-sulfenyl)-piperidin；1-[(Propan-2-yl)sulfanyl]piperidine；1-propan-2-ylsulfanylpiperidine
• CAS: 61076-33-3
• 化学式: C₈H₁₇NS
• 分子量: 159.296
• InChiKey: UHUNOYNQUXAGNP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  28.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  哌啶 、 isopropylsulfenyl chloride 在 2-甲基丁烷 作用下， 生成 1-isopropylsulfanyl-piperidine
  参考文献：
  名称：

  Alkyl thiosulfenamides and process of producing them

  摘要：

  公开号：

  US02807615A1

文献信息

• USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE
  申请人：Children's Medical Center Corporation

  公开号：US20210236632A1

  公开（公告）日：2021-08-05

  Provided herein are Toll-like receptor 2 (TLR2) agonists for use in enhancing human immune response and/or as adjuvants in vaccines. The TLR2 agonists include thiophenes, imidazoles, or phenyl-containing compounds, which may be compounds of Formulae (I), (II), (III), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. The compounds described herein are used as enhancers of an immune response (e.g., innate and/or adaptive immune response), and are useful in treating and/or preventing a disease, as adjuvants in a vaccine for the disease, (e.g., proliferative disease, inflammatory disease, autoimmune disease, infectious disease, or chronic disease). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
• [EN] FOXM1 INHIBITOR COMPOSITIONS AND METHODS OF USING THE SAME<br/>[FR] COMPOSITIONS À BASE D'UN INHIBITEUR DE FOXM1 ET PROCÉDÉS D'UTILISATION CORRESPONDANTES
  申请人：UNIV ILLINOIS

  公开号：WO2019199863A1

  公开（公告）日：2019-10-17

  Provided are compounds, or pharmaceutically acceptable salts thereof, which are useful for inhibiting FOXM1, inhibiting cancer growth, and/or treating cancer. In particular, these compounds and their corresponding quaternary ammonium salts may be used to treat various forms of breast cancer.
• [EN] INHIBITORS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS<br/>[FR] INHIBITEURS DU VIRUS DU SYNDROME REPRODUCTEUR ET RESPIRATOIRE PORCIN
  申请人：UNIV CONNECTICUT

  公开号：WO2021243118A1

  公开（公告）日：2021-12-02

  Disclosed herein are compositions comprising a compound of Formula (I) and methods for treating or prophylaxis of porcine reproductive and respiratory syndrome (PRRS) therewith (I).
• Alkyl thiosulfenamides and process of producing them
  申请人：PHILLIPS PETROLEUM CO

  公开号：US02807615A1

  公开（公告）日：1957-09-24