N6,O2',O3'-Triacetyladenosin-5-phosphat-pyridinium | 58377-26-7

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: N6,O2',O3'-Triacetyladenosin-5-phosphat-pyridinium
• 英文别名: N⁶,O²',O³'-Triacetyladenosin-5-phosphat-pyridinium
• CAS: 58377-26-7
• 化学式: C₅H₅N*C₁₆H₂₀N₅O₁₀P
• 分子量: 552.437
• InChiKey: PSCKUYMBZXSJQT-KHXPSBENSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.74
• 重原子数：
  38.0
• 可旋转键数：
  7.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  214.18
• 氢给体数：
  3.0
• 氢受体数：
  13.0

反应信息

• 作为反应物：
  描述：

  硬脂醇 、 N6,O2',O3'-Triacetyladenosin-5-phosphat-pyridinium 生成 ammonium salt of adenosine 5'-phosphate P-(1-octadecyl) ester
  参考文献：
  名称：

  Smrt, Jiri; Hynie, Sixtus, Collection of Czechoslovak Chemical Communications, 1980, vol. 45, # 3, p. 927 - 932

  摘要：

  DOI：

文献信息

• Effects of 3′-<i>C</i>-Methylation on the Hydrolytic Stability and Hydroxyl p<i>K</i>_aValues of Dinucleoside 2′,5′- and 3′,5′-Monophosphates
  作者：Mikko Oivanen、Ekaterina V. Efimtseva、Sergey N. Mikhailov

  DOI：10.1080/07328319808003471

  日期：1998.8

  The first-order rate constants for hydrolysis of 3'-C-methyluridylyl(2',5')- and -(3',5')adenosine and the corresponding native dinucleoside monophosphates (2',5'- and 3',5'-UpA) have been determined as a function of hydroxide-ion concentration (0.025 - 7 M) at 25 degrees C. In addition to the effects on the hydrolytic stability of the compounds, the effects of the 3'-C-methyl substitution on the kinetically determined pK(a) values for the sugar hydroxyls of the uridine moiety are discussed.