Xanthosine-monophosphate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: Xanthosine-monophosphate
• 英文别名: [5-(2,6-dioxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• 化学式: C₁₀H₁₃N₄O₉P
• 分子量: 364.21
• InChiKey: DCTLYFZHFGENCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  193
• 氢给体数：
  6
• 氢受体数：
  10

文献信息

• Variant phosphoribosylpyrophosphate amidotransferase and method of preparing purine nucleotide using the same
  申请人：CJ CHEILJEDANG CORPORATION

  公开号：US11008599B2

  公开（公告）日：2021-05-18

  Provided are a variant phosphoribosylpyrophosphate amidotransferase, a microorganism including the same, and a method of preparing a purine nucleotide using the same.

  本文提供了一种变异型磷酸核糖基焦磷酸酯脒基转移酶、一种包括该酶的微生物，以及一种使用该酶制备嘌呤核苷酸的方法。
• Promoter and method for producing purine nucleotide using the same
  申请人：CJ CHEILJEDANG CORPORATION

  公开号：US11041181B2

  公开（公告）日：2021-06-22

  The present disclosure relates to a polynucleotide having a novel promoter activity, a composition for expressing a gene comprising the polynucleotide, a microorganism comprising the gene, and a method for preparing purine nucleotides using the microorganism.

  本公开涉及一种具有新型启动子活性的多核苷酸、一种用于表达包含该多核苷酸的基因的组合物、一种包含该基因的微生物以及一种利用该微生物制备嘌呤核苷酸的方法。
• ELUCIDATING LIGAND-BINDING INFORMATION BASED ON PROTEIN TEMPLATES
  申请人：Skolnick Jeffrey

  公开号：US20110098238A1

  公开（公告）日：2011-04-28

  A method, computer-readable medium, and system for identifying compounds from chemical libraries that can be used for the therapeutic treatment of a disease or used as lead compounds in a drug development program. In particular, information from homologous proteins is used to predict, for a target protein, molecular functions that can be used to screen libraries of compounds for individual compounds that are predicted to have high binding affinities for the target protein.
• NOVEL PROMOTER AND METHOD FOR PRODUCING PURINE NUCLEOTIDE USING THE SAME
  申请人：CJ CHEILJEDANG CORPORATION

  公开号：US20210047665A1

  公开（公告）日：2021-02-18

  The present disclosure relates to a polynucleotide having a novel promoter activity, a composition for expressing a gene comprising the polynucleotide, a microorganism comprising the gene, and a method for preparing purine nucleotides using the microorganism.
• VARIANT PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE AND METHOD OF PREPARING PURINE NUCLEOTIDE USING THE SAME
  申请人：CJ CHEILJEDANG CORPORATION

  公开号：US20210047666A1

  公开（公告）日：2021-02-18

  Provided are a variant phosphoribosylpyrophosphate amidotransferase, a microorganism including the same, and a method of preparing a purine nucleotide using the same.