2,3-Di-O-methylellagic acid | 52600-48-3

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: 2,3-Di-O-methylellagic acid
• 英文别名: 6,7-dihydroxy-13,14-dimethoxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione
• CAS: 52600-48-3
• 化学式: C₁₆H₁₀O₈
• 分子量: 330.24
• InChiKey: DMPZOHHHRRENRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  112
• 氢给体数：
  2
• 氢受体数：
  8

文献信息

• TOPICAL AGENT FOR DERMATOLOGICAL USE
  申请人：Nakayama Hiroki

  公开号：US20110014141A1

  公开（公告）日：2011-01-20

  The objective of the present invention was to enhance the skin whitening effects and blackening prevention effects and supply safe and stable topical agents for dermatological use. For that purpose 4-Hydroxyphenyl-α-D-glucopyranoside was combined with auxiliary agents such as ascorbic acid and its derivatives, crude drugs and its extracts, hydroxycarboxylic acid and its salts, oil soluble glycyrrhiza extract, gentian extract, phenol derivatives and their salts, placenta extract, kojic acid and its derivatives, glucosamine and its derivatives, azelaic acid and its derivatives, retinol and its derivatives, pyridoxin and its derivatives, tocopherol and its derivatives, chitosan and its decomposition products, caffeic acid derivatives, hydroxycinnamate and its derivatives, Umbelliferae plant extracts, mycelial cultures and their extracts, plant leaves and their extracts.

  本发明的目的是增强皮肤美白效果和黑色素生成的预防效果，并提供安全稳定的用于皮肤科的局部制剂。为此，4-羟基苯基-α-D-葡萄糖苷与辅助剂如抗坏血酸及其衍生物、天然药物及其提取物、羟基羧酸及其盐、油溶性甘草提取物、龙胆提取物、酚类衍生物及其盐、胎盘提取物、曲酸及其衍生物、葡萄糖胺及其衍生物、癸二酸及其衍生物、视黄醇及其衍生物、吡哆醇及其衍生物、生育酚及其衍生物、壳聚糖及其分解产物、咖啡酸衍生物、羟基肉桂酸及其衍生物、伞形科植物提取物、菌丝培养物及其提取物、植物叶片及其提取物相结合。
• Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside
  申请人：PENTAPHARM Ltd.

  公开号：EP1859835A2

  公开（公告）日：2007-11-28

  The objective of the present invention was to enhance the skin whitening effects and blackening prevention effects and supply safe topical agents for dermatological use. For that purpose a topical composition comprising 4-hydroxyphenyl-alpha-D-glucopyranoside and UV absorber is manufactured.

  本发明的目的是增强皮肤美白效果和防止变黑效果，并提供安全的皮肤病外用制剂。为此，制造了一种由 4-羟基苯基-α-D-吡喃葡萄糖苷和紫外线吸收剂组成的外用组合物。
• PHARMACEUTICAL PREPARATION FOR EXTERNAL APPLICATION TO SKIN COMPRISING PHOSPHORYLATED SUGAR
  申请人：Ezaki Glico Co., Ltd.

  公开号：EP1932514A1

  公开（公告）日：2008-06-18

  Provided is an external preparation for skin, comprising a phosphorylated saccharide. The phosphorylated saccharide may be an inorganic salt of a phosphorylated saccharide. The phosphorylated saccharide may be a calcium, magnesium, potassium, zinc, iron or sodium salt. Also provided is an external preparation for skin, comprising a phosphorylated saccharide and a second component, wherein the second component is selected from the group consisting of moisturizing agents, whitening components, ultraviolet absorbents, anti-inflammatory agents, cell-activating agents and antioxidants. The moisturizing agent may be ascorbic acid or an ascorbic acid derivative.

  本文提供了一种皮肤外用制剂，其中包含一种磷酸化糖。磷酸化糖可以是磷酸化糖的无机盐。磷酸化糖可以是钙、镁、钾、锌、铁或钠盐。还提供了一种皮肤外用制剂，包括磷酸化糖和第二种成分，其中第二种成分选自保湿剂、美白成分、紫外线吸收剂、消炎剂、细胞活化剂和抗氧化剂组成的组。保湿剂可以是抗坏血酸或抗坏血酸衍生物。
• 皮膚外用組成物
  申请人：——

  公开号：JP2000247863A

  公开（公告）日：2000-09-12

  (57)【要約】\n【解決手段】 エラグ酸系化合物及び／又はその塩と、ヘパリン、ヘパリノイド及びこれらの塩から選ばれる少なくとも１種以上のヘパリン類とを配合してなる皮膚外用組成物。\n【効果】 エラグ酸系化合物やその塩からなる美白成分にヘパリン、ヘパリノイド及びこれらの塩から選ばれる少なくとも１種以上のヘパリン類とを併用することにより、上記美白成分による美白効果が向上して優れた美白効果を有するのみならず、特にニキビ痕に対して優れた美白効果を発揮すると共に、その安定性にも優れる皮膚外用組成物を提供することができる。

  (57) [摘要]n[溶液]一种用于皮肤局部应用的组合物，该组合物由鞣花酸化合物和/或其盐与至少一种或多种选自肝素、肝素类及其盐类的肝素结合而成。\通过将由鞣花酸化合物和/或其盐组成的美白成分与至少一种或多种选自肝素、肝素类化合物及其盐类的肝素结合，不仅提高了上述美白成分的美白效果，而且具有极佳的美白效果，尤其是对痤疮疤痕的美白效果此外，还能提供一种稳定性极佳的外用皮肤组合物。
• Flexible solid cosmetic composition comprising anionic surfactants and polymer conditioning agents, and cosmetic treatment method
  申请人：L'OREAL

  公开号：US10548832B2

  公开（公告）日：2020-02-04

  The present invention relates to an aqueous cosmetic composition in flexible solid form, comprising: at least 12 wt.-% of one or more anionic surfactants, and one or more polymer conditioning agents, said composition comprising at least one anionic surfactant selected from among acyl isethionates. The composition is preferably suitable for use as a composition for cleaning or washing keratin materials, particularly hair. The invention also relates to a cosmetic treatment method intended in particular for the care, cleaning and/or conditioning of keratin materials using said composition.

  本发明涉及一种柔性固体形式的水性化妆品组合物，包括 至少 12 wt.-%的一种或多种阴离子表面活性剂，以及 一种或多种聚合物调节剂、 所述组合物包括至少一种选自酰基异硫酸盐的阴离子表面活性剂。 该组合物最好适用于清洁或清洗角蛋白材料，尤其是头发。 本发明还涉及一种美容处理方法，特别是使用所述组合物对角蛋白材料进行护理、清洁和/或调理。