2-[3,5-Dimethoxy-4-(2,4,6-trimethoxyphenyl)phenoxy]-5-methoxybenzene-1,3-diol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: 2-[3,5-Dimethoxy-4-(2,4,6-trimethoxyphenyl)phenoxy]-5-methoxybenzene-1,3-diol
• 化学式: C₂₄H₂₆O₉
• 分子量: 458.5
• InChiKey: KXLQIKPTSXCHGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  33
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  9

文献信息

• Ascophyllum Compositions and Methods
  申请人：Zhang Junzeng

  公开号：US20080280994A1

  公开（公告）日：2008-11-13

  The invention provides extracts of brown seaweed of the genus Ascophyllum that have valuable pharmacological properties. In particular, compositions of the invention are useful for e.g.: inhibiting alpha-glucosidase activity; preventing or treating conditions mediated by alpha-glucosidase activity; reducing blood glucose levels; preventing or treating diabetes; modulating glucose uptake in adipocytes; preventing or treating obesity; scavenging free radicals; stimulating the immune system; activating macrophages; preventing or treating condition mediated by macrophage activation; and modulating nitric oxide production by macrophages. Methods for using the Ascophyllum extracts of the invention are provided, as are kits comprising Ascophyllum extracts of the invention and instructions for using the extracts.