3,4,5,11,19,20,21,24,25,36,37,40,41,42,52,53,54-Heptadecahydroxy-9,12,15,27,34,46,49-heptaoxaundecacyclo[49.3.1.02,7.010,48.013,47.017,22.023,32.026,31.029,38.030,35.039,44]pentapentaconta-1(55),2,4,6,17,19,21,23,25,29,31,35,37,39,41,43,51,53-octadecaene-8,16,28,33,45,50-hexone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: 3,4,5,11,19,20,21,24,25,36,37,40,41,42,52,53,54-Heptadecahydroxy-9,12,15,27,34,46,49-heptaoxaundecacyclo[49.3.1.02,7.010,48.013,47.017,22.023,32.026,31.029,38.030,35.039,44]pentapentaconta-1(55),2,4,6,17,19,21,23,25,29,31,35,37,39,41,43,51,53-octadecaene-8,16,28,33,45,50-hexone
• 化学式: C₄₈H₂₈O₃₀
• 分子量: 1084.7
• InChiKey: MVJJDNSSMDZLJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  78
• 可旋转键数：
  0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  511
• 氢给体数：
  17
• 氢受体数：
  30

文献信息

• Anti-resorptive and bone building dietary supplements and methods of use
  申请人：Krempin David W.

  公开号：US20080199545A1

  公开（公告）日：2008-08-21

  Disclosed herein are dietary supplement compositions and methods for increasing or stimulating bone growth, decreasing or preventing bone resorption, increasing bone strength, improving bone structure, and improving bone architecture comprising a first composition comprising a combination of at least two of: quercetin, Rehmannia sp., Rehmannia sp. root, Siberian ginseng, Sophora japonica , licorice, and ipriflavone, wherein the combination of the first composition increases bone morphogenic protein-2 gene, promoter or protein expression; and a second composition comprising an extract of pomegranate in combination with at least one of Siberian ginseng, Ginkgo biloba , green tea, Sophora japonica, Rehmannia sp., grape seed, Dong Quai, and ipriflavone, wherein the combination of the second composition inhibits the expression of RANK-L.
• Topical Composition with Skin Lightening Effect
  申请人：Rana Jatinder

  公开号：US20110038968A1

  公开（公告）日：2011-02-17

  A topical cosmetic composition for increasing skin whitening or lightening is described. The composition includes a pomegranate extract in an amount effective to reduce melanin composition. The pomegranate extract may be standardized to about 20% punicalagin. The composition may also include an extract from the genus larix, such as Larix sibirica. The larix sibirica may be standardized to 80% taxifolin. A method for using the compositions is described.
• Anti-Resorptive and Bone Building Dietary Supplements and Methods of Use
  申请人：Murray Mary A.

  公开号：US20160346344A1

  公开（公告）日：2016-12-01

  Disclosed herein are dietary supplement compositions and methods for increasing or stimulating bone growth, decreasing or preventing bone resorption, increasing bone strength, improving bone structure, and improving bone architecture comprising a first composition comprising a combination of at least two of: quercetin, Rehmannia sp., Rehmannia sp. root, Siberian ginseng, Sophora japonica , licorice, and ipriflavone, wherein the combination of the first composition increases bone morphogenic protein-2 gene, promoter or protein expression; and a second composition comprising an extract of pomegranate in combination with at least one of Siberian ginseng, Ginkgo biloba , green tea, Sophora japonica, Rehmannia sp., grape seed, Dong Quai, and ipriflavone, wherein the combination of the second composition inhibits the expression of RANK-L.
• US7897184B1
  申请人：——

  公开号：US7897184B1

  公开（公告）日：2011-03-01
• US8202556B2
  申请人：——

  公开号：US8202556B2

  公开（公告）日：2012-06-19