2-[[9-[3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: 2-[[9-[3,4-Dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid
• 化学式: C₁₄H₁₈N₅O₁₁P
• 分子量: 463.29
• InChiKey: OFBHPPMPBOJXRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.2
• 重原子数：
  31
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  247
• 氢给体数：
  7
• 氢受体数：
  15

文献信息

• PROANGIOGENIC COMPOSITIONS AND METHODS OF USE
  申请人：University of North Dakota

  公开号：US20210277005A1

  公开（公告）日：2021-09-09

  Various embodiments disclosed relate to a pharmaceutical composition. The composition includes the structure according to Formula I or pharmaceutically acceptable ester thereof, prodrug thereof, or a pharmaceutically acceptable salt thereof: In Formula I, R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 , are independently selected from the group consisting of —H, —OH, —COOH, and substituted or unsubstituted (C 1 -C 20 )hydrocarbyl.