Emblicanin A | 180465-44-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: Emblicanin A
• 英文别名: [3,4,5,21,22,23-hexahydroxy-8,13,18-trioxo-12-(3,4,5-trihydroxybenzoyl)oxy-9,14,17-trioxatetracyclo[17.4.0.02,7.010,15]tricosa-1(23),2,4,6,11,19,21-heptaen-11-yl] 3,4,5-trihydroxybenzoate
• CAS: 180465-44-5
• 化学式: C₃₄H₂₂O₂₂
• 分子量: 782.5
• InChiKey: UEHSSTYZXFBDNL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  56
• 可旋转键数：
  6
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  374
• 氢给体数：
  12
• 氢受体数：
  22

文献信息

• Method for protecting mitochondria in retina cell
  申请人：TAIWAN MITOCHONDRION APPLIED TECHNOLOGY CO.,LTD.

  公开号：US10967019B2

  公开（公告）日：2021-04-06

  A use of an emblica extract in preparing a pharmaceutical composition for protecting mitochondria in retina is provided. When the pharmaceutical composition, which comprises the emblica extract, is provided to retinal cells, a use of the pharmaceutical composition comprises improvement of the ability of performing the oxidative phosphorylation for the synthesis of the adenosine triphosphate (ATP) by the mitochondria in the retinal cells under or exposed to ultraviolet light, and improvement of the coupling efficiency of the synthesis of the adenosine triphosphate by the mitochondria.

  本发明提供了一种在制备用于保护视网膜线粒体的药物组合物中使用白芷提取物的方法。当向视网膜细胞提供包含该白芷提取物的药物组合物时，该药物组合物的用途包括提高视网膜细胞线粒体在紫外线下或暴露于紫外线下合成三磷酸腺苷（ATP）的氧化磷酸化能力，以及提高线粒体合成三磷酸腺苷的耦合效率。
• OPTIMAL BIOLOGICAL MARKER FOR THE BIOLOGICAL POTENCY OF Emblica Officinalis Gaertn. (AMLA) FRUIT-METHODS AND PRODUCTS THEREOF
  申请人：Majeed Muhammed

  公开号：US20100062989A1

  公开（公告）日：2010-03-11

  Disclosed is the most optimal biomarker for the BIOLOGICAL POTENCY of Emblica Officinalis Gaertn. (Amla) fruit and products standardized for 5% and above w/w of the said biomarker. Further, the products described herein contain from about 0.00010% to about 4% of free ascorbic acid depending on the raw material used. The optimal biomarker for amla described herein above is represented by STR#1.
• Antioxidant Compositions, Beverage Formulations Thereof, and Methods of Increasing Antioxidant Capability
  申请人：McNeary Peter S.

  公开号：US20100215783A1

  公开（公告）日：2010-08-26

  Compositions including synergistic combinations of ascorbic acid, Indian gooseberry, and additional components for increasing the antioxidant capability of certain target components, such as superfruits, fruits, and other low and/or high antioxidant containing substances. Particular combinations of ascorbic acid, Indian gooseberry extract, one or more citrus bioflavanoids, and one or more fatty acids added to various target components synergistically increases the antioxidant capability of the overall composition over expected values.
• METHOD FOR IMPROVING MITOCHONDRIA AND METHOD FOR PROMOTING CELL DIVISION OF STEM CELL
  申请人：TAIWAN MITOCHONDRION APPLIED TECHNOLOGY CO.,LTD.

  公开号：US20170151297A1

  公开（公告）日：2017-06-01

  The present disclosure is related to a method for improving mitochondria in a cell, comprising step of treating the cell with an extraction of Emblica officinalis, for improving ability of mitochondria to perform oxidative phosphorylation and synthesize adenosine triphosphate. The present disclosure is also related to a method for promoting proliferation of a stem cell, comprising step of treating the stem cell with an extraction of Emblica officinalis, for improving division rate of the stem cell.
• USE OF EMBLICA EXTRACT IN PREPARING PHARMACEUTICAL COMPOSITION FOR PROTECTING MITOCHONDRIA IN RETINA
  申请人：TAIWAN MITOCHONDRION APPLIED TECHNOLOGY CO.,LTD.

  公开号：US20180008657A1

  公开（公告）日：2018-01-11

  A use of an emblica extract in preparing a pharmaceutical composition for protecting mitochondria in retina is provided. When the pharmaceutical composition, which comprises the emblica extract, is provided to retinal cells, a use of the pharmaceutical composition comprises improvement of the ability of performing the oxidative phosphorylation for the synthesis of the adenosine triphosphate (ATP) by the mitochondria in the retinal cells under or exposed to ultraviolet light, and improvement of the coupling efficiency of the synthesis of the adenosine triphosphate by the mitochondria.