Ethyl 2-oxoimidazole-4-carboxylate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: Ethyl 2-oxoimidazole-4-carboxylate
• 化学式: C₆H₆N₂O₃
• 分子量: 154.12
• InChiKey: VCAIPSUUTZJHRP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  68.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• UROCANIC ACID DERIVATIVES USEFUL FOR THE TREATMENT OF IMMUNE-RELATED AND INFLAMMATORY DISEASES
  申请人：Kammeijer Arthur

  公开号：US20100197752A1

  公开（公告）日：2010-08-05

  The invention relates to derivatives of urocanic acid that have improved efficacy and/or tissue penetration properties. The invention further provides use of these derivatives in a medicament for modulating an immune-related disease in an individual. Imidazole derivative, or a salt thereof, selected from O I1 W—C—R1 H— (formula 1); o I1 W—C—R1 and HN N r<1 NH (formula 2); O O Ov ̂ W—C—R1 and HN N (formula 3);