5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 生物素及其衍生物
• 英文名称: 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
• 英文别名: 5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
• 化学式: C₁₀H₁₇N₃O₂S
• 分子量: 243.33
• InChiKey: XFLVBMBRLSCJAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  110
• 氢给体数：
  3
• 氢受体数：
  3

文献信息

• [EN] NEW TECHNOLOGY TO CONJUGATE THE TACCALONOLIDE MICROTUBULE STABILIZERS WITH LINKERS/PAYLOADS<br/>[FR] NOUVELLE TECHNOLOGIE POUR CONJUGUER LES STABILISATEURS TACCALONOLIDES DE MICROTUBULES AVEC DES LIEURS/CHARGES UTILES
  申请人：DU LIN

  公开号：WO2020185610A1

  公开（公告）日：2020-09-17

  The present disclosure is concerned with taccalonolide analogs and conjugated taccalonolide analogs useful as cellular probes and in the treatment of, for example, hyperproliferative disorders such as cardiovascular diseases and cancer. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本公开涉及可用作细胞探针和用于治疗高增殖性疾病，如心血管疾病和癌症的塔卡龙内酯类似物和共轭塔卡龙内酯类似物。本摘要旨在作为在特定领域搜索的扫描工具，并不意味着对本发明的限制。
• [EN] BIOCONJUGATES WITH A CONTROLLED DEGREE OF CONJUGATION, THEIR PROCESS OF PREPARATION, AND THE REAGENTS FOR THEIR PREPARATION<br/>[FR] BIOCONJUGUÉS PRÉSENTANT UN DEGRÉ DE CONJUGAISON RÉGULÉ, LEUR PROCÉDÉ DE PRÉPARATION ET RÉACTIFS POUR LEUR PRÉPARATION
  申请人：CENTRE NAT RECH SCIENT

  公开号：WO2019008164A1

  公开（公告）日：2019-01-10

  The present invention relates to a process for preparation of heterogeneous monodisperse mixtures of protein conjugates with a defined degree of conjugation (1-8) obtained by using a tri-functional reagent allowing affinity concentration followed by subsequent simultaneous release-functionalization.

  本发明涉及一种制备蛋白共轭物的异质单分散混合物的方法，其具有定义的结合度（1-8），通过使用一种三功能试剂进行亲和浓缩，然后进行后续同时释放功能化。
• MACROLIDE COMPOUNDS CONTAINING BIOTIN AND PHOTO-AFFINITY GROUP FOR MACROLIDE TARGET IDENTIFICATION
  申请人：Glaxo Group Limited

  公开号：EP1836212B1

  公开（公告）日：2011-09-07
• Method for the synthesis of a bifunctional complex
  申请人：Nuevolution A/S

  公开号：EP2348125B1

  公开（公告）日：2017-06-21
• METHOD FOR FABRICATING PATTERN ON A BIOSENSOR SUBSTRATE AND BIOSENSOR USING THE SAME
  申请人：HONG Hyobong

  公开号：US20090283426A1

  公开（公告）日：2009-11-19

  The present invention relates to a method for fabricating a pattern on a biosensor substrate and a biosensor using the same. The present invention provides a method of fabricating a pattern on a substrate of a biosensor in which an amine group is formed on a substrate by using polyethylenimine (PEI), and a site to which a biosubstance is immobilized is masked and irradiated with ultraviolet rays, such that a pattern having a desired shape can be formed on the substrate and a biosensor in which the biosubstance is immobilized on the pattern acquired by using the above-mentioned method.