2-[4-[4-[4-[4-[4-[4-[2-[4-[2-[2-[2-[4-[2-[4-(3,5-Dihydroxyphenoxy)-2,6-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-2,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-2,6-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]benzene-1,3,5-triol

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: 2-[4-[4-[4-[4-[4-[4-[2-[4-[2-[2-[2-[4-[2-[4-(3,5-Dihydroxyphenoxy)-2,6-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-2,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-2,6-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]benzene-1,3,5-triol
• 英文别名: 2-[4-[4-[4-[4-[4-[4-[2-[4-[2-[2-[2-[4-[2-[4-(3,5-dihydroxyphenoxy)-2,6-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-2,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-4,6-dihydroxyphenoxy]-2,6-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]-3,5-dihydroxyphenoxy]benzene-1,3,5-triol
• 化学式: C₉₆H₆₆O₄₈
• 分子量: 1987.5
• InChiKey: YMOIZYZRBLAFFF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  13.1
• 重原子数：
  144
• 可旋转键数：
  30
• 环数：
  16.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  806
• 氢给体数：
  33
• 氢受体数：
  48

文献信息

• NOVEL COMPOUND HEXADECAPHLORETHOL ISOLATED FROM ISHIGE OKAMURAE AND USE THEREOF
  申请人：Jeju National University Industry-Academic Cooperation Foundation

  公开号：US20200157031A1

  公开（公告）日：2020-05-21

  Disclosed herein are hexadecaphlorethol (HdP), which is a novel compound isolated from Ishige okamurae , and the use thereof in anti-diabetic treatment and exercise performance improvement. The novel compound HdP has the activity of inhibiting α-glucosidase, inducing glucose uptake into differentiated myoblast C2C12 cells, reducing blood glucose levels in zebrafish which have reduced insulin secretion through treatment with alloxan, increasing an intracellular level of calcium ions necessary for muscle contraction and exercise performance in zebrafish, and inducing uptake of glucose, an energy source necessary for muscle contraction, into cells.