5-(1-哌啶基)-3-戊炔-1-醇 | 104580-60-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 中文名称: 5-(1-哌啶基)-3-戊炔-1-醇
• 英文名称: 5-piperidino-1-pent-3-yn-1-ol
• 英文别名: 5-(Piperidin-1-yl)pent-3-yn-1-ol；5-piperidin-1-ylpent-3-yn-1-ol
• CAS: 104580-60-1
• 化学式: C₁₀H₁₇NO
• mdl: MFCD02012810
• 分子量: 167.251
• InChiKey: VGLQDXKMJHPROT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2933399090

反应信息

• 作为产物：
  描述：

  二哌啶甲烷 、 3-丁炔-1-醇 在 copper(l) chloride 作用下， 反应 6.0h， 以92%的产率得到5-(1-哌啶基)-3-戊炔-1-醇
  参考文献：
  名称：

  Aminomethylation of acetylene alcohols and their esters with gem-diamines catalyzed by complexes of d-transition and rare-earth metals

  摘要：

  An efficient synthetic procedure was developed for preparation of oxygen-containing propargylamines with high yields and selectivity by aminomethylation of propargyl alcohols and their esters with gem-diamines catalyzed by complexes and salts of d-transition metals and lanthanides.

  DOI：

  10.1134/s1070428011020023

文献信息

• AGABABAYAN, R. G.;XRIMYAN, A. P.;BADANYAN, SH. O., ARM. XIM. ZH., 1985, 38, N 6, 364-369
  作者：AGABABAYAN, R. G.、XRIMYAN, A. P.、BADANYAN, SH. O.

  DOI：——

  日期：——
• Aminomethylation of acetylene alcohols and their esters with gem-diamines catalyzed by complexes of d-transition and rare-earth metals
  作者：M. G. Shaibakova、I. G. Titova、A. G. Ibragimov、U. M. Dzhemilev

  DOI：10.1134/s1070428011020023

  日期：2011.2

  An efficient synthetic procedure was developed for preparation of oxygen-containing propargylamines with high yields and selectivity by aminomethylation of propargyl alcohols and their esters with gem-diamines catalyzed by complexes and salts of d-transition metals and lanthanides.