trimethylsilyl N-methylcarbamate | 51094-24-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: trimethylsilyl N-methylcarbamate
• 英文别名: trimethylsilyl methylcarbamate；N-Methylcarbamidsaeuretrimethylester；Trimethylsilyl-methylcarbamat
• CAS: 51094-24-7
• 化学式: C₅H₁₃NO₂Si
• mdl: MFCD19216944
• 分子量: 147.249
• InChiKey: MLFYURWOWYWXKQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2931900090

反应信息

• 作为反应物：
  描述：

  trimethylsilyl N-methylcarbamate 生成 N-methyl-N-trimethylsilylcarbamic acid trimethylsilyl ester
  参考文献：
  名称：

  KNAUSZ, D.;MESZTICZKY, A.;SZAKACS, L.;CSAKVARI, B.;UJSZASZY, K., J. ORGANOMET. CHEM., 1983, 256, N 1, 11-21

  摘要：

  DOI：
• 作为产物：
  描述：

  三甲基氯硅烷 、 甲基氨基甲酸甲胺 以 二氯甲烷 为溶剂， 反应 0.5h， 生成 trimethylsilyl N-methylcarbamate
  参考文献：
  名称：

  三甲基甲硅烷基化的N-烷基取代的氨基甲酸酯I.制备及一些反应

  摘要：

  三甲基甲硅烷Ñ -monoalkyl-和Ñ，Ñ二烷基-氨基甲酸酯已在85-95％的收率由相应的氨基甲酸铵与三甲基氯硅烷的甲硅烷基化制备。三甲基甲硅烷基N N-二甲基氨基甲酸酯可用于醇，酚和羧酸的甲硅烷基化。甲硅烷基氨基甲酸酯与羧酸卤化物反应，得到相应的酸酰胺。氨基甲酸三甲基甲硅烷基酯与羧酸酐的反应生成相应的甲硅烷基羧酸酯和酰胺，而与二羧酸酐的反应生成相应的二羧酸的三甲基甲硅烷基单酰胺，即Me 3 SiO 2 -CCONR 1 R2。

  DOI：

  10.1016/s0022-328x(00)99291-x
• 作为试剂：
  描述：

  苯基三氯硅烷 在 trimethylsilyl N-methylcarbamate 作用下， 以18%的产率得到1,3,5,7-Tetraphenyl-hexachlor-tetrasiloxan
  参考文献：
  名称：

  Sheludyakov, V. D.; Dmitrieva, A. B.; Tumanov, V. Yu., Journal of general chemistry of the USSR, 1982, vol. 52, p. 1907 - 1908

  摘要：

  DOI：

文献信息

• ——
  作者：L. K. Kibardina、M. A. Pudovik、A. N. Pudovik

  DOI：10.1023/a:1012336429887

  日期：——

  Bis(chloromethyl)phosphinic chloride reacts with trimethylsilyl methylcarbamate in benzene in the presence of a base to give trimethylsilyl bis(chloromethyl)phosphinate. The same reaction performed without a solvent and in the absence of a base yields trimethylsilyl bis(chloromethyl)phosphinate and bis(chloromethyl)phosphinic anhydride. Reaction of bis(chloromethyl)phosphinic chloride with trimethylsilyl diethylcarbamate yields N,N-diethylbis(chloromethyl)phosphinic amide. The reaction of bis(chloromethyl)phosphinic (-phosphinothioic) chlorides with trimethylsilyl N-trimethylsilylacetimidoate was studied.
• Organosilicon synthesis of isocyanates: II. Synthesis of aliphatic, carbocyclic, and fatty-aromatic isocyanates
  作者：A. V. Lebedev、A. B. Lebedeva、V. D. Sheludyakov、S. N. Ovcharuk、E. A. Kovaleva、O. L. Ustinova

  DOI：10.1134/s1070363206030182

  日期：2006.3

  Silylation of a series of aliphatic, carbocyclic, and fatty-aromatic amines gave the corresponding silyl derivatives whose yield depended on the electronic and steric structure of the substrate and the nature of the silylating agent. The yield of isocyanates obtained by phosgenation of the silyl derivatives under mild conditions decreased in going from aliphatic amines to benzylamines and rose as the length of the alkyl chain in fatty-aromatic amines extended. The most convenient procedure for the synthesis of low-boiling alkyl isocyanates was found to be based on the transformation of amines or ammonium salts into silyl or silyl silyl-carabamates. followed by pyrolysis of the latter in the presence of trichloro(phenyl)silane.
• Mironov,V.F. et al., Journal of general chemistry of the USSR, 1975, vol. 45, p. 1971 - 1973
  作者：Mironov,V.F. et al.

  DOI：——

  日期：——
• The reaction of chloromethylsilanes with amines, hexamethyldisilazanes, and silylcarhamates
  作者：A. D. Kirilin、N. B. Sokova、E. A. Chernyshev

  DOI：10.1007/bf00703492

  日期：1994.10

  The reactions of chloromethylsilanes with amines, hexamethyldisilazane, and silylcarbamates were studied. The dependence of the composition and structure of the resulting products on the nature of the reagents used and reaction conditions was determined. A scheme for the synthesis of 4,9-diaza-2,7-dioxa-1,6-disilacyclodecane-3,8-dione derivatives was suggested.
• Sheludyakov,V.D. et al., Journal of general chemistry of the USSR, 1976, vol. 46, p. 2589 - 2594
  作者：Sheludyakov,V.D. et al.

  DOI：——

  日期：——