2-benzoyl-5-methoxyphenyl benzoate | 21112-63-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: 2-benzoyl-5-methoxyphenyl benzoate
• 英文别名: 2-Benzoyloxy-4-methoxy-benzophenon；5-Methoxy-2-(phenylcarbonyl)phenyl benzoate；(2-benzoyl-5-methoxyphenyl) benzoate
• CAS: 21112-63-0
• 化学式: C₂₁H₁₆O₄
• 分子量: 332.356
• InChiKey: PTKZNHIKPCVSCK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  紫外线吸收剂 UV-9 、 苯甲醇 在 叔丁基过氧化氢 、 copper diacetate 作用下， 以 水 、 二甲基亚砜 为溶剂， 反应 20.0h， 以88%的产率得到2-benzoyl-5-methoxyphenyl benzoate
  参考文献：
  名称：

  Cu(II)-catalyzed oxidative esterification of 2-carbonyl substituted phenols from the alcohol oxidation level

  摘要：

  A copper-catalyzed oxidative esterification of 2-carbonyl substituted phenols from the alcohol oxidation level is described. This protocol represents direct access to a range of 2-carbonylated aryl benzoate derivatives, which are important building blocks in the synthesis of natural and pharmacological compounds. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.08.079

文献信息

• Derivatives of 2,4-dihydroxybenzophenone. Part I
  作者：Frank S. H. Head

  DOI：10.1039/j39690000034

  日期：——

  Several 4-(β-aryloxyethyl), 4-(β-aryloxyethoxymethyl and 4-[β-(aryloxymethoxy)ethyl] ethers of 2,4-dihydroxy-benzophenone are reported; such are frequently dimorphic. An easy preparation of 4-hydroxy-2-methoxy-benzophenone is described.

  据报道有几种2,4-二羟基二苯甲酮的4-（β-芳氧基乙基），4-（β-芳氧基乙氧基甲基）和4- [β-（芳氧基甲氧基）乙基]醚；它们经常是二态的，易于制备4-羟基描述了-2-甲氧基-二苯甲酮。
• Cu(II)-catalyzed oxidative esterification of 2-carbonyl substituted phenols from the alcohol oxidation level
  作者：Satyasheel Sharma、Jihye Park、Mirim Kim、Jong Hwan Kwak、Young Hoon Jung、In Su Kim

  DOI：10.1016/j.tet.2013.08.079

  日期：2013.11

  A copper-catalyzed oxidative esterification of 2-carbonyl substituted phenols from the alcohol oxidation level is described. This protocol represents direct access to a range of 2-carbonylated aryl benzoate derivatives, which are important building blocks in the synthesis of natural and pharmacological compounds. (C) 2013 Elsevier Ltd. All rights reserved.