sodium hydroxymethanesulfonate | 16434-10-9

• 分子结构分类: 有机化合物 - 有机盐 - 有机金属盐
• 英文名称: sodium hydroxymethanesulfonate
• 英文别名: formaldehyde sodium bisulfite adduct；Sodium;hydroxymethyl sulfite
• CAS: 16434-10-9
• 化学式: CH₃O₄S*Na
• 分子量: 134.088
• InChiKey: GMWLMJGJIBESBF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -4.25
• 重原子数：
  7
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  88.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  sodium hydroxymethanesulfonate 在 hydroxide 作用下， 生成 hydroxycarbene
  参考文献：
  名称：

  Pulse radiolysis study of the reaction of hydroxyl radicals with methanesulfonate and hydroxymethanesulfonate

  摘要：

  Pulse radiolysis studies of the reaction kinetics of methanesulfonate and hydroxymethanesulfonate with hydroxyl radicals were conducted by relative rate methods. The rate constant for the reaction of CH3SO3- with OH. was determined as 1.24 (+/- 0.07) x 10(7) M-1 s-1 at an ionic strength of 0.2 M, with thiocyanate as the reference solute. For the same ionic strength conditions, the rate constant for the attack of OH. with CH2(OH)SO3-, k = 2.65 (+/- 0.12) x 10(8) M-1 s-1, was more than an order of magnitude greater than the rate constant for methanesulfonate. Previous estimates of the rate constants for the methanesulfonate reaction varied by approximately 2 orders of magnitude; our results are in best agreement with the slowest value. Our rate constant for hydroxymethanesulfonate was also significantly smaller than two previously reported values. Both reactions are independent of pH over the pH range studied (3.8-6.5) and are nearly independent of ionic strength. These results imply that the oxidation of methanesulfonate by OH. is too slow to be significant in typical remote cloud droplets, but may be important in aerosols. The reaction of OH. with hydroxymethanesulfonate would be significant in atmospheric droplets when hydroxyl radical concentrations are at least 10(-12) M.

  DOI：

  10.1021/j100187a027

文献信息

• A General Synthesis of 3,5-Dihalo-2<i>H</i>-1,4-oxazin-2-ones from Cyanohydrins
  作者：Lieven Meerpoel、Georges Hoornaert

  DOI：10.1055/s-1990-27049

  日期：——

  In a novel approach starting from O-trimethylsilyl protected or unprotected cyanohydrins and oxalyl chloride or bromide, a series of unknown 6-substituted 3,5-dihalo-2H-1,4-oxazin-2-ones were prepared. The method was shown to be efficient for various types of cyanohydrins; however cyclization was not obtained with cyanohydrins containing bulky substituents, electron-rich aryl or heteroaryl groups. A mechanism is proposed.

  从O-三甲基硅烷保护或未保护的氰醇以及草酰氯或溴开始，采用一种新颖的方法合成了一系列未知的6-取代-3,5-二卤代-2H-1,4-恶嗪-2-酮。该方法对各种类型的氰醇都显示出高效性；然而，对于含有大体积取代基、富电子芳基或杂芳基的氰醇，未能实现环化反应。提出了一个可能的反应机理。
• Pulse radiolysis study of the reaction of hydroxyl radicals with methanesulfonate and hydroxymethanesulfonate
  作者：Terese M. Olson、Richard W. Fessenden

  DOI：10.1021/j100187a027

  日期：1992.4

  Pulse radiolysis studies of the reaction kinetics of methanesulfonate and hydroxymethanesulfonate with hydroxyl radicals were conducted by relative rate methods. The rate constant for the reaction of CH3SO3- with OH. was determined as 1.24 (+/- 0.07) x 10(7) M-1 s-1 at an ionic strength of 0.2 M, with thiocyanate as the reference solute. For the same ionic strength conditions, the rate constant for the attack of OH. with CH2(OH)SO3-, k = 2.65 (+/- 0.12) x 10(8) M-1 s-1, was more than an order of magnitude greater than the rate constant for methanesulfonate. Previous estimates of the rate constants for the methanesulfonate reaction varied by approximately 2 orders of magnitude; our results are in best agreement with the slowest value. Our rate constant for hydroxymethanesulfonate was also significantly smaller than two previously reported values. Both reactions are independent of pH over the pH range studied (3.8-6.5) and are nearly independent of ionic strength. These results imply that the oxidation of methanesulfonate by OH. is too slow to be significant in typical remote cloud droplets, but may be important in aerosols. The reaction of OH. with hydroxymethanesulfonate would be significant in atmospheric droplets when hydroxyl radical concentrations are at least 10(-12) M.