N-(β-piperidino)ethylurea | 98487-61-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: N-(β-piperidino)ethylurea
• 英文别名: (2-piperidino-ethyl)-urea；(2-Piperidino-aethyl)-harnstoff；N-[2-Piperidin-1-ylethyl]urea；2-piperidin-1-ylethylurea
• CAS: 98487-61-7
• 化学式: C₈H₁₇N₃O
• 分子量: 171.242
• InChiKey: FDAWBMYJDPMZIA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  58.4
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-(β-piperidino)ethylurea 、 硫酸二甲酯 在 乙醇 作用下， 生成 1-methyl-1-(2-ureido-ethyl)-piperidinium; methyl sulfate
  参考文献：
  名称：

  Quaternary ammonium compound

  摘要：

  公开号：

  US02203505A1
• 作为产物：
  描述：

  2-piperidinoethylphthalimide 在 盐酸 作用下， 生成 N-(β-piperidino)ethylurea
  参考文献：
  名称：

  Chiti; Selleri, Farmaco, Edizione Scientifica, 1957, vol. 12, p. 551,568

  摘要：

  DOI：

文献信息

• [EN] PURINE DERIVATIVES<br/>[FR] DERIVES DE PURINE
  申请人：PFIZER LTD

  公开号：WO2002000676A1

  公开（公告）日：2002-01-03

  The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts and solvates thereof, to processes for the preparation of, intermediates used in the preparation of, and compositions containing such compounds and the uses of such compounds as adenosine A2a receptor agonists.

  本发明涉及式（I）化合物及其药学上可接受的盐和溶剂化物，制备过程中使用的中间体，以及含有此类化合物的组合物和将此类化合物用作腺苷A2a受体激动剂的用途。
• Reactive catalyst compositions for improving water blown polyurethane foam performance
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0877042A1

  公开（公告）日：1998-11-11

  The present invention provides a reactive catalyst composition for making a water blown flexible polyurethane foam. The catalyst composition comprises a tertiary amino alkyl urea and/or bis(tertiary amino alkyl) urea in combination with either a gelling catalyst or blowing catalyst. The use of such catalyst composition improves the physical properties of the polyurethane foam.

  本发明提供了一种用于制造水发泡软质聚氨酯泡沫的活性催化剂组合物。该催化剂组合物由叔氨基烷基脲和/或双叔氨基烷基脲与胶凝催化剂或发泡催化剂组合而成。使用这种催化剂组合物可以改善聚氨酯泡沫塑料的物理性能。
• Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP1443065A1

  公开（公告）日：2004-08-04

  The present invention relates to an improvement in flexible, semi-flexible and rigid foams formed by the catalytic reaction of an aromatic polyisocyanate, a polyol and a blowing agent and a process for preparing such polyisocyanate. The improvement resides in using an effective amount of a bismuth carboxylate or bismuth sulfonate having less than 34% free acid as the catalyst.

  本发明涉及芳香族多异氰酸酯、多元醇和发泡剂催化反应形成的软质、半软质和硬质泡沫的改进，以及制备这种多异氰酸酯的工艺。改进之处在于使用了有效量的游离酸小于 34% 的羧酸铋或磺酸铋作为催化剂。
• Fast demold/extended cream time polyurethane formulations
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP1600465A2

  公开（公告）日：2005-11-30

  Catalyst compositions for use in forming polyurethane products include a gelling catalyst, a trimerization catalyst, and a cure accelerator. The gelling catalyst is a tertiary amine, mono(tertiary amino) urea, bis(tertiary amino) urea, or a combination of any of these. Any known trimerization catalyst may be used. The cure accelerator may be a diol having at least one primary hydroxyl group, and having from five to 17 chain backbone atoms chosen from carbon, oxygen, or both between the hydroxyl groups, provided that at least five of the backbone atoms are carbon. Alternatively or in addition, the cure accelerator may be a polyol having three or more hydroxyl groups, at least two of which are primary, and having molecular weights between 90 g/mole and 400 g/mole. Delayed initiation of the polyurethane-forming reaction and/or reduced demold time for producing the polyurethane part can be obtained by using these catalyst compositions.

  用于形成聚氨酯产品的催化剂组合物包括胶凝催化剂、三聚催化剂和固化促进剂。胶凝催化剂是一种叔胺、单（叔氨基）脲、双（叔氨基）脲或其中任何一种的组合。也可使用任何已知的三聚催化剂。固化促进剂可以是具有至少一个伯羟基的二元醇，在羟基之间具有 5 至 17 个碳原子、氧原子或两者兼有的链骨架原子，但至少有五个骨架原子是碳原子。另外，固化促进剂可以是具有三个或三个以上羟基（其中至少两个是伯羟基）的多元醇，分子量在 90 克/摩尔到 400 克/摩尔之间。使用这些催化剂组合物可以延迟聚氨酯成型反应的开始时间和/或缩短生产聚氨酯 部件的脱模时间。
• Catalyst compositions for improving polyurethane foam performance
  申请人：Air Products and Chemicals, Inc.

  公开号：EP1867669A1

  公开（公告）日：2007-12-19

  The present invention provides a reactive catalyst composition for making a water blown flexible polyurethane foam. The catalyst composition comprises one or more tertiary amine catalysts in combination with (1) 2-methyl-1,3-propanediol or (2) a blend of 2-methyl-1,3-propanediol and a C7+ alkanol. The use of such catalyst composition improves the physical properties of the polyurethane foam.

  本发明提供了一种用于制造水发泡软质聚氨酯泡沫的活性催化剂组合物。该催化剂组合物由一种或多种叔胺催化剂与 (1) 2-甲基-1,3-丙二醇或 (2) 2-甲基-1,3-丙二醇和 C7+ 烷醇的混合物组成。使用这种催化剂组合物可改善聚氨酯泡沫的物理性能。