[5-((E)-2-Chloro-1,2-difluoro-vinyl)-thiophen-2-yl]-trimethyl-silane | 76892-18-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩类
• 英文名称: [5-((E)-2-Chloro-1,2-difluoro-vinyl)-thiophen-2-yl]-trimethyl-silane
• CAS: 76892-18-7
• 化学式: C₉H₁₁ClF₂SSi
• 分子量: 252.788
• InChiKey: JKGMPAWKGKEXMN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14.0
• 可旋转键数：
  2.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0.0
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  三甲基甲硅烷 、 [5-((E)-2-Chloro-1,2-difluoro-vinyl)-thiophen-2-yl]-trimethyl-silane 反应 1.0h， 以70%的产率得到trimethylsilyl 2-(1,2-difluoro-2-chlorovinyl)thiophene-5-sulfonate
  参考文献：
  名称：

  Starostina, T. A.; Rybakova, L. F.; Shifrina, R. R., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, # 9, p. 1678 - 1681

  摘要：

  DOI：
• 作为产物：
  描述：

  2-(三甲基硅基)噻吩 在 正丁基锂 作用下， 以 乙醚 为溶剂， 生成 [5-((E)-2-Chloro-1,2-difluoro-vinyl)-thiophen-2-yl]-trimethyl-silane
  参考文献：
  名称：

  Starostina, T. A.; Rybakova, L. F.; Shifrina, R. R., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, # 9, p. 1678 - 1681

  摘要：

  DOI：

文献信息

• Synthesis of Conjugated <i>F</i>-Polyenes Containing Thienyl Ring Systems
  作者：Alexander B. Shtarev、Zdeněk Chvátal

  DOI：10.1021/jo962325x

  日期：1997.8.1

  Novel 1-substituted F-1,3-butadienes ThioAr-CF=CFCF=CF2, ThioAr = 2-thienyl and 2-benzo[b]thienyl, and symmetrically 1,4-disubstituted F-1,3-butadienes ThioAr-CF=CFCF=CF-ThioAr, ThioAr = 5-R'-2-thienyl (R' = Me, SiMe3, CF=CFCl), 3-thienyl, and 4-dibenzo[b,d]thienyl, inclusive of the above-named substituents, were prepared by the reaction of organolithium derivatives with F-1,3-butadiene (PFBD). Monothioaryl-substituted F-1,3-butadienes were used as intermediates in subsequent reactions with other (thioaryl)organolithium derivatives for the synthesis of a new series of unsymmetrically substituted alpha,omega-bis(thioaryl)-F-polyenes ThioAr-(CF=CF)(n)-ThioAr', where n = 2, ThioAr, ThioAr' = 4-RC2H4 (R = H, Me, OC6H11, NMe2), 2-thienyl, 5-methyl-2-thienyl, 2-benzo[b]thienyl, 4-dibenzo[b,d]thienyl, and for n = 3, ThioAr = 2-thienyl, ThioAr' = 5-methyl-2-thienyl. The reaction of 2,5-dilithiothiophene with 1-(2-thienyl)-F-1,3-butadiene affords 2,5-bis-[4-(2-thienyl)-1,2,3,4-tetrafluoro-1,3-butadienyl]thiophene (5). 2,5-Thienylene-F-polyenylene polymers were prepared by the reaction of 2,5-dilithio- and 2,5-bis(bromomagnesio)thiophene derivatives with PFBD and F-ethylene. The oligomers 5 and 2,5-bis[2-(2-thienyl)-1,2-difluoroethylenyl]- thiophene (16) were found to possess liquid crystalline properties. The reaction of 1,4-bis(2-thienyl)-F-1,3-butadiene with nitric acid led to substitution in one or in both thienyl rings at position 5. NMR, electronic spectra, and structural aspects of the title compounds are discussed.
• Starostina, T. A.; Rybakova, L. F.; Shifrina, R. R., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, # 9, p. 1678 - 1681
  作者：Starostina, T. A.、Rybakova, L. F.、Shifrina, R. R.

  DOI：——

  日期：——