CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS
申请人:ENCYSIVE PHARMACEUTICALS, INC
公开号:EP1176956B1
公开(公告)日:2008-01-09
US7812038B2
申请人:——
公开号:US7812038B2
公开(公告)日:2010-10-12
Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
申请人:——
公开号:US20040063955A1
公开(公告)日:2004-04-01
A method for the inhibition of the binding of &agr;
4
&bgr;
1
integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which &agr;
4
&bgr;
1
is involved.