2-[cyclohexyl(trimethylsiloxy)methyl]-1-dodecene | 1192889-73-8

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2-[cyclohexyl(trimethylsiloxy)methyl]-1-dodecene
• 英文别名: (1-Cyclohexyl-2-methylidenedodecoxy)-trimethylsilane
• CAS: 1192889-73-8
• 化学式: C₂₂H₄₄OSi
• 分子量: 352.676
• InChiKey: DPNVCYZUAFWZDO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.87
• 重原子数：
  24
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (Z)-1-(trimethylsilyl)dodec-1-ene 、 环己烷基甲醛 在 manganese(II) iodide 、 platinum(II) chloride 作用下， 以 1,2-二氯乙烷 为溶剂， 以71%的产率得到2-[cyclohexyl(trimethylsiloxy)methyl]-1-dodecene
  参考文献：
  名称：

  Platinum-Catalyzed Nucleophilic Addition of Vinylsilanes at the β-Position

  摘要：

  In the presence of catalytic amounts of PtCl(2) and metal iodides, beta-substituted vinylsilanes reacted with aldehydes at the beta-position to give allyl silyl ethers. The Pt-catalyzed addition to aromatic aldehydes proceeded efficiently in the presence of Lil. The combined use of PtCl(2) and Mnl(2) was found to be effective in addition to aliphatic aldehydes.

  DOI：

  10.1021/ol902060r

文献信息

• Platinum-Catalyzed Nucleophilic Addition of Vinylsilanes at the β-Position
  作者：Katsukiyo Miura、Gen Inoue、Hisashi Sasagawa、Hidenori Kinoshita、Junji Ichikawa、Akira Hosomi

  DOI：10.1021/ol902060r

  日期：2009.11.5

  In the presence of catalytic amounts of PtCl(2) and metal iodides, beta-substituted vinylsilanes reacted with aldehydes at the beta-position to give allyl silyl ethers. The Pt-catalyzed addition to aromatic aldehydes proceeded efficiently in the presence of Lil. The combined use of PtCl(2) and Mnl(2) was found to be effective in addition to aliphatic aldehydes.