Thiopropionsaeure-isobutylamid | 5827-76-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫代酰胺
• 英文名称: Thiopropionsaeure-isobutylamid
• 英文别名: N-isobutyl-thiopropionamide；N-Isobutyl-thiopropionamid；Thiopropionyl-isobutylamin；N-(2-methylpropyl)propanethioamide
• CAS: 5827-76-9
• 化学式: C₇H₁₅NS
• mdl: MFCD19219526
• 分子量: 145.269
• InChiKey: GNBUONXPONYBOS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  44.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  异硫氰酸异丁酯 、 三乙基铝 以 苯 为溶剂， 生成 Thiopropionsaeure-isobutylamid
  参考文献：
  名称：

  Reinheckel,H. et al., Chemische Berichte, 1966, vol. 99, p. 11 - 22

  摘要：

  DOI：

文献信息

• Sakurada, Bulletin of the Chemical Society of Japan, 1927, vol. 2, p. 308
  作者：Sakurada

  DOI：——

  日期：——
• OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING
  申请人：Suzuki Hideyuki

  公开号：US20100256355A1

  公开（公告）日：2010-10-07

  The present invention provides a novel oxazolidinone derivative of the formula (I): wherein Ring A is (A-1) a 7-membered monocyclic heterocycle containing three N atoms; (A-2) a 7-membered monocyclic heterocycle containing two N atoms and one O atom; or (A-3) a 7-membered monocyclic heterocycle containing two N atoms and one S atom, SO or SO 2 , wherein said monocyclic heterocycle is optionally substituted, optionally unsaturated and optionally fused with another ring; X 1 is a single bond, or a heteroatom-containing group selected from the group consisting of —O—, —S—, —NR 2 —, —CO—, —CS—, —CONR 3 —, —NR 4 CO—, —SO 2 NR 5 —, and —NR 6 SO 2 —, wherein R 2 , R 3 , R 4 , R 5 and R 6 are independently hydrogen or lower alkyl, or lower alkylene or lower alkenylene each optionally interrupted by said heteroatom-containing group; Ring B is optionally substituted carbocycle or optionally substituted heterocycle; and R 1 is hydrogen, or an organic residue which is able to bind to the 5 -position of the oxazolidinone ring in oxazolidinone antimicrobial agents, pharmaceutically acceptable salts and solvates thereof which are useful as an antibacterial agent.
• US8530646B2
  申请人：——

  公开号：US8530646B2

  公开（公告）日：2013-09-10
• Reinheckel,H. et al., Chemische Berichte, 1966, vol. 99, p. 11 - 22
  作者：Reinheckel,H. et al.

  DOI：——

  日期：——