1-Dimethyl(phenyl)silyloxy-10-undecene

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 1-Dimethyl(phenyl)silyloxy-10-undecene
• 英文别名: dimethyl-phenyl-undec-10-enoxysilane
• 化学式: C₁₉H₃₂OSi
• 分子量: 304.548
• InChiKey: DMHJDDDTPQOBFY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.42
• 重原子数：
  21
• 可旋转键数：
  12
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.58
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  10-十一烯醛 、 二甲基苯基硅烷 在 Stryker's reagent 作用下， 以 甲苯 为溶剂， 反应 2.0h， 以95%的产率得到1-Dimethyl(phenyl)silyloxy-10-undecene
  参考文献：
  名称：

  Hydrosilylation of aldehydes and ketones catalyzed by [Ph3P(CuH)]6

  摘要：

  Exposure of an aldehyde or ketone to less than or equal to 5 mol% (in copper) of Stryker's reagent [Ph3P(CuH)](6) in the presence of one of several silanes affords the corresponding protected alcohol in high yields. Aldehydes can be cleanly reduced in the presence of ketones. (C) 2001 Elsevier Science B.V, AH rights reserved.

  DOI：

  10.1016/s0022-328x(00)00903-7

文献信息

• A Highly Chemoselective Cobalt Catalyst for the Hydrosilylation of Alkenes using Tertiary Silanes and Hydrosiloxanes
  作者：Abdulrahman D. Ibrahim、Steven W. Entsminger、Lingyang Zhu、Alison R. Fout

  DOI：10.1021/acscatal.6b01091

  日期：2016.6.3

  The hydrosilylation of alkene substrates bearing additional functionalities is difficult to achieve using earth-abundant catalysts and has not been extensively realized with both earth-abundant transition metals and tertiary silanes or hydrosiloxanes. Reported herein is a well-defined bis(carbene) cobalt(I)-dinitrogen complex for the efficient, catalytic anti-Markovnikov hydrosilylation of terminal

  带有附加功能的烯烃底物的氢化硅烷化难以使用富含地球的催化剂来实现，并且还没有被富含地球的过渡金属和叔硅烷或氢硅氧烷广泛地实现。本文报道的是定义明确的双（卡宾）钴（I）-二氮配合物，用于末端烯烃的高效，催化抗马尔科夫尼科夫氢化硅烷化反应，具有广泛的底物范围。含有羟基，氨基，酯，环氧化物，酮，甲酰基和腈基的烯烃按该反应顺序被选择性地氢化硅烷化。反应性中间体的多核NMR研究提供了对该机理的见解。
• Hydrosilylation of aldehydes and ketones catalyzed by [Ph3P(CuH)]6
  作者：Bruce H Lipshutz、Will Chrisman、Kevin Noson

  DOI：10.1016/s0022-328x(00)00903-7

  日期：2001.4

  Exposure of an aldehyde or ketone to less than or equal to 5 mol% (in copper) of Stryker's reagent [Ph3P(CuH)](6) in the presence of one of several silanes affords the corresponding protected alcohol in high yields. Aldehydes can be cleanly reduced in the presence of ketones. (C) 2001 Elsevier Science B.V, AH rights reserved.