肌苷-5'-磷酸单钠盐 | 5375-41-7

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 中文名称: 肌苷-5'-磷酸单钠盐
• 英文名称: inosine-5'-phosphate monosodium salt
• 英文别名: inosine 5'-phosphate sodium salt；sodium 5'-inosinate；Inosin-5'-Phosphat-natriumsalz；Inosine-5'-monophosphate disodium salt；sodium;[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methyl hydrogen phosphate
• CAS: 5375-41-7
• 化学式: C₁₀H₁₂N₄O₈P*Na
• 分子量: 370.191
• InChiKey: PZGQXGXEKACEEW-MCDZGGTQSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -5.37
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  183
• 氢给体数：
  4
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  肌苷-5'-磷酸单钠盐 、 以 not given 为溶剂， 生成 Na2[Cu(inosine-5'-monophosphate)2(imidazole)0.8(H2O)1.2(H2O)2]*12.4H2O
  参考文献：
  名称：

  Poojary, M. Damodara; Manohar, Inorganic Chemistry, 1985, vol. 24, # 7, p. 1065 - 1069

  摘要：

  DOI：

文献信息

• Kois, Pavol; Holy, Antonin, Collection of Czechoslovak Chemical Communications, 1980, vol. 45, # 10, p. 2830 - 2838
  作者：Kois, Pavol、Holy, Antonin

  DOI：——

  日期：——
• MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF
  申请人：FERRER INTERNACIONAL, S.A.

  公开号：US20220160744A1

  公开（公告）日：2022-05-26

  The present invention relates to a multilayer pharmaceutical or nutraceutical solid dosage form comprising at least one pyrimidine derivative, purine derivative or any salt or solvate thereof and least one B-group vitamin. It also provides three methods for producing said multilayer pharmaceutical or nutraceutical solid dosage forms. Furthermore, the present invention is also related to therapeutic uses of said multilayer pharmaceutical or nutraceutical solid dosage forms, particularly for the treatment and/or prevention of peripheral neuropathy.
• [EN] MULTILAYER PHARMACEUTICAL OR NUTRACEUTICAL SOLID DOSAGE FORMS COMPRISING PYRIMIDINE AND/OR PURINE DERIVATIVES AND B VITAMINS, PREPARATION AND USES THEREOF<br/>[FR] FORMES POSOLOGIQUES SOLIDES PHARMACEUTIQUES OU NUTRACEUTIQUES MULTICOUCHES COMPRENANT DES DÉRIVÉS DE PYRIMIDINE ET/OU DE PURINE ET DES VITAMINES B, LEUR PRÉPARATION ET LEURS UTILISATIONS
  申请人：FERRER INT

  公开号：WO2020224795A1

  公开（公告）日：2020-11-12

  The present invention relates to a multilayer pharmaceutical or nutraceutical solid dosage form comprising at least one pyrimidine derivative, purine derivative or any salt or solvate thereof and least one B-group vitamin. It also provides three methods for producing said multilayer pharmaceutical or nutraceutical solid dosage forms. Furthermore, the present invention is also related to therapeutic uses of said multilayer pharmaceutical or nutraceutical solid dosage forms, particularly for the treatment and/or prevention of peripheral neuropathy.