Benzyl 4-[4-[[4-(4-methoxy-4-oxo-1-phenylbutan-2-yl)pyrimidin-2-yl]amino]phenyl]piperazine-1-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: Benzyl 4-[4-[[4-(4-methoxy-4-oxo-1-phenylbutan-2-yl)pyrimidin-2-yl]amino]phenyl]piperazine-1-carboxylate
• 英文别名: benzyl 4-[4-[[4-(4-methoxy-4-oxo-1-phenylbutan-2-yl)pyrimidin-2-yl]amino]phenyl]piperazine-1-carboxylate
• 化学式: C₃₃H₃₅N₅O₄
• 分子量: 565.7
• InChiKey: RHBNDDQXQQKCFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  42
• 可旋转键数：
  12
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  96.9
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• VEGFR3 INHIBITORS
  申请人：CANCER THERAPEUTICS CRC PTY LIMITED

  公开号：US20140080798A1

  公开（公告）日：2014-03-20

  This invention relates to compounds of the formula (I): The invention also relates to processes for the preparation of the compound of the formula (I), pharmaceutical agents or compositions containing the compound or a method of using the compound for the treatment of proliferative diseases, such as cancer, as well as the treatment of diseases ameliorated by the control and/or inhibition of lymphangiogenesis.

  本发明涉及公式（I）的化合物。该发明还涉及制备公式（I）化合物的方法，含有该化合物的药物制剂或组合物，或使用该化合物治疗增生性疾病（如癌症）以及通过控制和/或抑制淋巴管生成改善疾病的方法。
• TEMPLATED METAL PARTICLES AND METHODS OF MAKING
  申请人：Wendland Michael S.

  公开号：US20080152911A1

  公开（公告）日：2008-06-26

  Composite particles of a metal particle within a crosslinked, cored dendrimer are described. Additionally, methods of making the composite particles and compositions that contain the composite particles are described.
• US9266864B2
  申请人：——

  公开号：US9266864B2

  公开（公告）日：2016-02-23