(8-Diazospiro[4.5]dec-3-en-4-yl) ethyl carbonate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 英文名称: (8-Diazospiro[4.5]dec-3-en-4-yl) ethyl carbonate
• 英文别名: (8-diazospiro[4.5]dec-3-en-4-yl) ethyl carbonate
• 化学式: C13H18N2O3
• 分子量: 250.29
• InChiKey: VSGXFHOTGSJVNG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.69
• 拓扑面积：
  37.5
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS<br/>[FR] DÉRIVÉS DE QUINOLÉINE DESTINÉS AU TRAITEMENT D'INFECTIONS PAR DES HELMINTHES
  申请人：BAYER ANIMAL HEALTH GMBH

  公开号：WO2019025341A1

  公开（公告）日：2019-02-07

  The present invention covers quinoline compounds of general formula (I), in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.

  本发明涵盖了通式（I）所示的喹啉化合物，其中A、R1、R2、R3、R4、R5、R6和Q的定义如本文所述，制备所述化合物的方法，用于制备所述化合物的中间体化合物，包含所述化合物的药物组合物和组合物，以及利用所述化合物制造用于治疗、控制和/或预防疾病的药物组合物，特别是蠕虫感染，作为单一药剂或与其他活性成分组合使用。
• [EN] ISOQUINOLINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARASITIC INFECTIONS<br/>[FR] DÉRIVÉS D'ISOQUINOLÉINE ET LEUR UTILISATION DANS LE TRAITEMENT D'INFECTIONS PARASITAIRES
  申请人：BAYER ANIMAL HEALTH GMBH

  公开号：WO2021018839A1

  公开（公告）日：2021-02-04

  The present invention covers new isoquinoline compounds of general formula (I), in which A, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.

  本发明涵盖了一般式（I）的新异喹啉化合物，其中A、R1、R2、R3、R4、R5、R6和Q的定义如本文所述，制备所述化合物的方法，用于制备所述化合物的中间体化合物，包括所述化合物的药物组合物和组合物，以及利用所述化合物制造用于治疗、控制和/或预防疾病的药物组合物的用途，特别是蠕虫感染，作为唯一药剂或与其他活性成分组合使用。
• [EN] NEW AZAQUINOLINE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS D'AZAQUINOLINE
  申请人：BAYER ANIMAL HEALTH GMBH

  公开号：WO2019002132A1

  公开（公告）日：2019-01-03

  The present invention covers azaquinoline compounds of general formula (I), with A being (A1) or (A2), and in which T, R1, R2, R3, R4, R5, R6, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.

  本发明涵盖了一般式(I)的氮杂喹啉化合物，其中A为(A1)或(A2)，其中T、R1、R2、R3、R4、R5、R6和Q的定义如本文所述，以及制备所述化合物的方法，用于制备所述化合物的有用中间体化合物，包括所述化合物的药物组合物和组合物，以及利用所述化合物制造用于治疗、控制和/或预防疾病的药物组合物，特别是蠕虫感染，作为单一药剂或与其他活性成分结合。
• [EN] NEW BICYCLIC PYRAZOLE DERIVATIVES<br/>[FR] NOUVEAUX DÉRIVÉS BICYCLIQUES DE PYRAZOLE
  申请人：BAYER ANIMAL HEALTH GMBH

  公开号：WO2018197401A1

  公开（公告）日：2018-11-01

  The present invention covers bicyclic pyrazole compounds of general formula (I) : in which G, A, R1, R2, R3, and Q are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment, control and/or prevention of diseases, in particular of helminth infections, as a sole agent or in combination with other active ingredients.

  本发明涵盖了通式（I）的双环吡唑化合物：其中G、A、R1、R2、R3和Q的定义如本文所述，以及制备该化合物的方法，用于制备该化合物的中间体化合物，包含该化合物的制药组合物和药物组合物，以及使用该化合物制备用于治疗、控制和/或预防疾病的制药组合物，特别是针对寄生虫感染的疾病，作为唯一的药物或与其他活性成分组合使用。
• COMPOSITIONS COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE
  申请人：Bayer CropScience AG

  公开号：EP2854529A1

  公开（公告）日：2015-04-08