2,2-dioxo-5-(piperidin-3-ylmethoxy)-1H-2lambda6,1,3-benzothiadiazin-4-amine;hydrochloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻二嗪
• 英文名称: 2,2-dioxo-5-(piperidin-3-ylmethoxy)-1H-2lambda6,1,3-benzothiadiazin-4-amine;hydrochloride
• 英文别名: 2,2-dioxo-5-(piperidin-3-ylmethoxy)-1H-2λ6,1,3-benzothiadiazin-4-amine;hydrochloride
• 化学式: C13H19ClN4O3S
• 分子量: 346.83
• InChiKey: NKRNRFJHAQLTCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.86
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  114
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• [EN] SWEET FLAVOR MODIFIER<br/>[FR] MODIFICATEUR D'ARÔME ÉDULCORANT
  申请人：SENOMYX INC

  公开号：WO2014025706A1

  公开（公告）日：2014-02-13

  The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

  本发明包括具有结构式（I）的化合物，或其盐或溶剂合物。这些化合物可用作甜味调味剂。本发明还包括包含本化合物的组合物以及调节组合物甜味的方法。
• [EN] 5-SUBSTITUTED 4-AMINO-1H-BENZO[C][1,2,6]THIADIAZINE 2,2-DIOXIDES AND FORMULATIONS AND USES THEREOF<br/>[FR] 4-AMINO-1 H-BENZO[C][1,2,6] THIADIAZINE 2,2-DIOXYDES 5-SUBSTITUÉS ET FORMULATIONS ET UTILISATIONS DE CEUX-CI
  申请人：FIRMENICH INCORPORATED

  公开号：WO2020033420A1

  公开（公告）日：2020-02-13

  Disclosed herein are 5-Substituted 4-amino-1H-benzo[c][1,2,6]thiadiazine 2,2-dioxide compounds useful as sweet flavor modifiers. Also disclosed herein are ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener.

  本文揭示了5-取代的4-氨基-1H-苯并[c][1,2,6]噻二嗪2,2-二氧化物化合物，可用作甜味调味剂。本文还揭示了包含这些化合物之一或多个与天然或人工甜味剂结合的可食用组合物。
• SWEET FLAVOR MODIFIER
  申请人：SENOMYX, INC.

  公开号：US20150031684A1

  公开（公告）日：2015-01-29

  The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

  本发明包括具有结构式(I)的化合物或其盐或溶剂合物。这些化合物可用作甜味调节剂。本发明还包括包含这些化合物的组合物和调节组合物甜味的方法。
• 5-SUBSTITUTED 4-AMINO-1H-BENZO[C][1,2,6]THIADIAZINE 2,2-DIOXIDES AND FORMULATIONS AND USES THEREOF
  申请人：Firmenich Incorporated

  公开号：EP3814344A1

  公开（公告）日：2021-05-05
• 5-SUBSTITUTED 4-AMINO-1H-BENZO[c][1,2,6]THIADIAZINE 2,2-DIOXIDES AND FORMULATIONS AND USES THEREOF
  申请人：Firmenich Incorporated

  公开号：US20210309654A1

  公开（公告）日：2021-10-07

  Disclosed herein are 5-Substituted 4-amino-1H-benzo[c] [1,2,6]thiadiazine 2,2-dioxide compounds useful as sweet flavor modifiers. Also disclosed herein are ingestible compositions that include one or more of these compounds in combination with a natural or artificial sweetener.