1-[(3S)-3-[(4-amino-2,2-dioxo-1H-2lambda6,1,3-benzothiadiazin-5-yl)oxymethyl]piperidin-1-yl]-2-(4-ethoxyphenyl)ethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻二嗪
• 英文名称: 1-[(3S)-3-[(4-amino-2,2-dioxo-1H-2lambda6,1,3-benzothiadiazin-5-yl)oxymethyl]piperidin-1-yl]-2-(4-ethoxyphenyl)ethanone
• 英文别名: 1-[(3S)-3-[(4-amino-2,2-dioxo-1H-2λ6,1,3-benzothiadiazin-5-yl)oxymethyl]piperidin-1-yl]-2-(4-ethoxyphenyl)ethanone
• 化学式: C₂₃H₂₈N₄O₅S
• 分子量: 472.6
• InChiKey: XIFUYMJRNJRNST-KRWDZBQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  33
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.39
• 拓扑面积：
  132
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• [EN] SWEET FLAVOR MODIFIER<br/>[FR] MODIFICATEUR D'ARÔME ÉDULCORANT
  申请人：SENOMYX INC

  公开号：WO2014025706A1

  公开（公告）日：2014-02-13

  The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

  本发明包括具有结构式（I）的化合物，或其盐或溶剂合物。这些化合物可用作甜味调味剂。本发明还包括包含本化合物的组合物以及调节组合物甜味的方法。
• SWEET FLAVOR MODIFIER
  申请人：SENOMYX, INC.

  公开号：US20150031684A1

  公开（公告）日：2015-01-29

  The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

  本发明包括具有结构式(I)的化合物或其盐或溶剂合物。这些化合物可用作甜味调节剂。本发明还包括包含这些化合物的组合物和调节组合物甜味的方法。
• METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER
  申请人：Senomyx, Inc.

  公开号：US20170119033A1

  公开（公告）日：2017-05-04

  Disclosed herein are stabilized sweet enhancer compositions. Also disclosed herein are methods for stabilizing sweet enhancers.
• SWEETENER COMPOSITION
  申请人：Senomyx, Inc.

  公开号：US20170354175A1

  公开（公告）日：2017-12-14

  Formulations comprising one or more sweetener and one or more flavor modifying compound are provided herein, wherein the formulation is provided for use in ingestible products, such as food or beverage products or pharmaceutical, or for use in non-comestible products, such as cosmetic or hygienic products.
• US8877922B2
  申请人：——

  公开号：US8877922B2

  公开（公告）日：2014-11-04