(R)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one | 1554633-18-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻二嗪
• 英文名称: (R)-1-(3-(((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)methyl)piperidin-1-yl)-3-methylbutan-1-one
• 英文别名: 1-[(3R)-3-[(4-amino-2,2-dioxo-1H-2lambda6,1,3-benzothiadiazin-5-yl)oxymethyl]piperidin-1-yl]-3-methylbutan-1-one；1-[(3R)-3-[(4-amino-2,2-dioxo-1H-2λ6,1,3-benzothiadiazin-5-yl)oxymethyl]piperidin-1-yl]-3-methylbutan-1-one
• CAS: 1554633-18-9
• 化学式: C₁₈H₂₆N₄O₄S
• 分子量: 394.495
• InChiKey: WATMWKUPIIWAGO-CYBMUJFWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  123
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• [EN] SWEET FLAVOR MODIFIER<br/>[FR] MODIFICATEUR D'ARÔME ÉDULCORANT
  申请人：SENOMYX INC

  公开号：WO2014025706A1

  公开（公告）日：2014-02-13

  The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

  本发明包括具有结构式（I）的化合物，或其盐或溶剂合物。这些化合物可用作甜味调味剂。本发明还包括包含本化合物的组合物以及调节组合物甜味的方法。
• SWEET FLAVOR MODIFIER
  申请人：SENOMYX, INC.

  公开号：US20150031684A1

  公开（公告）日：2015-01-29

  The present invention includes compounds having structural formula (I), or salts or solvates thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of modulating the sweet taste of compositions.

  本发明包括具有结构式(I)的化合物或其盐或溶剂合物。这些化合物可用作甜味调节剂。本发明还包括包含这些化合物的组合物和调节组合物甜味的方法。
• Beverages containing rare sugars
  申请人：The Coca-Cola Company

  公开号：US10849339B2

  公开（公告）日：2020-12-01

  Beverages comprising rare sugars and sweetness enhancers are provided herein, wherein the sweetness enhancers are present at or below the sweetness recognition threshold concentration. Also provided are methods for improving the sweetness of a beverage comprising rare sugars by adding a sweetness enhancer in a concentration at or below its sweetness recognition threshold. Beverages comprising natural high potency sweeteners and rare sugars with sugar-like characteristics are also provided, wherein the natural high potency sweetener and rare sugars are present in particular weight ratios.

  本文提供了由稀有糖和甜味增强剂组成的饮料，其中甜味增强剂的浓度达到或低于甜味识别阈值。此外，还提供了通过添加甜味增强剂，使其浓度达到或低于甜味识别阈值，从而改善包含稀有糖类的饮料甜度的方法。还提供了包含天然高效甜味剂和具有类糖特性的稀有糖的饮料，其中天然高效甜味剂和稀有糖以特定的重量比存在。
• US20140271996A1
  申请人：——

  公开号：US20140271996A1

  公开（公告）日：2014-09-18
• BEVERAGES CONTAINING RARE SUGARS
  申请人：The Coca-Cola Company

  公开号：US20170295827A1

  公开（公告）日：2017-10-19

  Beverages comprising rare sugars and sweetness enhancers are provided herein, wherein the sweetness enhancers are present at or below the sweetness recognition threshold concentration. Also provided are methods for improving the sweetness of a beverage comprising rare sugars by adding a sweetness enhancer in a concentration at or below its sweetness recognition threshold. Beverages comprising natural high potency sweeteners and rare sugars with sugar-like characteristics are also provided, wherein the natural high potency sweetener and rare sugars are present in particular weight ratios.