[5-(2,6-Diamino-3,6-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: [5-(2,6-Diamino-3,6-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• 英文别名: [5-(2,6-diamino-3,6-dihydropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
• 化学式: C₁₀H₁₇N₆O₇P
• 分子量: 364.25
• InChiKey: HQCCDSTTXROJAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.7
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  211
• 氢给体数：
  7
• 氢受体数：
  10

文献信息

• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE
  申请人：MODERNA THERAPEUTICS

  公开号：US20140010861A1

  公开（公告）日：2014-01-09

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH BLOOD AND LYMPHATIC DISORDERS
  申请人：Bancel Stephane

  公开号：US20140147432A1

  公开（公告）日：2014-05-29

  The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
• PHARMACEUTICAL COMPOSITION
  申请人：BARANOWITZ Steven

  公开号：US20170071966A1

  公开（公告）日：2017-03-16

  This invention relates to pharmaceutical compositions for oral administration to treat, for example, acute radiation sickness, wherein the composition comprises, for example, a first agent which is selected from the group consisting of beta-carotene, and pharmaceutically acceptable derivatives thereof; a therapeutically effective amount of a second agent which is selected from the group consisting of cholic acid, derivatives thereof, and pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable excipient.
• FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME
  申请人：MARS, INCORPORATED

  公开号：US20180168208A1

  公开（公告）日：2018-06-21

  A flavor composition comprising at least one nucleotide derivative and/or at least one transmembrane compound that modulates, increases and/or enhances the activity of an umami receptor is provided that can be used to enhance the umami taste and/or palatability of food products. In certain, non-limiting embodiments, the flavor composition comprises at least one nucleotide derivative and/or at least one transmembrane compound, optionally at least one nucleotide, optionally at least one first amino acid, optionally at least one second amino acid.
• US9220755B2
  申请人：——

  公开号：US9220755B2

  公开（公告）日：2015-12-29