[7-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl 2-methylprop-2-enoate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: [7-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl 2-methylprop-2-enoate
• 英文别名: [7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-2-oxo-3,4-dihydroquinolin-1-yl]methyl 2-methylprop-2-enoate
• 化学式: C₂₈H₃₃Cl₂N₃O₄
• 分子量: 546.5
• InChiKey: OEJWCZWKJCIPJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  37
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  62.3
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• [EN] PHARMACEUTICAL COMPOSITIONS HAVING IMPROVED STORAGE STABILITY<br/>[FR] COMPOSITIONS PHARMACEUTIQUES AYANT UNE PLUS GRANDE STABILITÉ AU STOCKAGE
  申请人：ALKERMES PHARMA IRELAND LTD

  公开号：WO2014080285A2

  公开（公告）日：2014-05-30

  The present invention relates to a pharmaceutical composition that provides long-term stability of a hydrolytically labile antipsychotic agent
• [EN] ARIPIPRAZOLE FORMULATIONS HAVING INCREASED INJECTION SPEEDS<br/>[FR] FORMULATIONS D'ARIPIPRAZOLE PRÉSENTANT DES VITESSES D'INJECTION PLUS ÉLEVÉES
  申请人：ALKERMES PHARMA IRELAND LTD

  公开号：WO2015143145A1

  公开（公告）日：2015-09-24

  The present invention relates to pharmaceutical compositions comprising a compound of Formula (I) that are useful for the intramuscular delivery of antipsychotic drugs using rapid injection rates.