3,5-Dichloro-2-methyl-1-benzofuran

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并呋喃
• 英文名称: 3,5-Dichloro-2-methyl-1-benzofuran
• 英文别名: 3,5-dichloro-2-methyl-1-benzofuran
• 化学式: C₉H₆Cl₂O
• 分子量: 201.05
• InChiKey: IZKMGMPHSBWXSG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  13.1
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF
  申请人：MERIAL, INC.

  公开号：US20160185726A1

  公开（公告）日：2016-06-30

  The present invention relates to novel anthelmintic compounds of formula (I) below: wherein Y and Z are independently a bicyclic carbocyclic or a bicyclic heterocyclic group, or one of Y or Z is a bicyclic carbocyclic or a bicyclic heterocyclic group and the other of Y or Z is alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heterocyclyl or heteroaryl, and variables X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 and X 8 are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.

  本发明涉及以下式子（I）的新型驱虫化合物：其中Y和Z分别是双环碳环或双环杂环基团，或者Y或Z是双环碳环或双环杂环基团，而Y或Z的另一个是烷基，烯基，炔基，环烷基，苯基，杂环基或杂环芳基，变量X1，X2，X3，X4，X5，X6，X7和X8如本文所定义。本发明还提供包含本发明的驱虫化合物的兽医组合物，并用于治疗和预防动物寄生虫感染。
• US9249102B2
  申请人：——

  公开号：US9249102B2

  公开（公告）日：2016-02-02
• [EN] ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF<br/>[FR] COMPOSÉS ET COMPOSITIONS ANTHELMINTHIQUES ET LEUR PROCÉDÉ D'UTILISATION
  申请人：MERIAL LTD

  公开号：WO2014081697A2

  公开（公告）日：2014-05-30

  The present invention relates to novel anthelmintic compounds of formula (I) wherein Y and Z are independently a bicyclic carbocyclic or a bicyclic heterocyclic group, or one of Y or Z is a bicyclic carbocyclic or a bicyclic heterocyclic group and the other of Y or Z is alkyl, alkenyl, alkynyl, cycloalkyl, phenyl, heterocyclyl or heteroaryl, and variables X1, X2, X3, X4, X5, X6, X7 and X8 are as defined herein. The invention also provides for veterinary compositions comprising the anthelmintic compounds of the invention, and their uses for the treatment and prevention of parasitic infections in animals.