N-[1-amino-3-(3,4-dihydroxyphenyl)-1-oxopropan-2-yl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 生物素及其衍生物
• 英文名称: N-[1-amino-3-(3,4-dihydroxyphenyl)-1-oxopropan-2-yl]-5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanamide
• 化学式: C₁₉H₂₆N₄O₅S
• 分子量: 422.5
• InChiKey: RSBSKNVXSXEUEC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  29
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  179
• 氢给体数：
  6
• 氢受体数：
  6

文献信息

• Method for marking or immobilising a target structure
  申请人：Szardenings Michael

  公开号：US20140162303A1

  公开（公告）日：2014-06-12

  Method for marking a target structure, comprising the following steps: a) providing a compound V that includes at least one dihydroxy- or trihydroxyphenyl group, b) providing a means for converting the dihydroxy- or trihydroxyphenyl group to a quinone group, c) providing a target structure, d) oxidising the dihydroxy- or trihydroxyphenyl group of the compound V to the quinone group, and e) contacting the compound V with the target structure, so that a covalent bond can be formed, wherein in step e) the compound V is used in a concentration such that the maximum concentration of dihydroxy-, trihydroxyphenyl groups and quinone groups that are introduced by the compound V is ≦500 μM, preferably ≦300 μM, and more preferably ≦100 μM.
• US9193986B2
  申请人：——

  公开号：US9193986B2

  公开（公告）日：2015-11-24