[(2R,3S,5R)-5-[6-(6-aminohexylamino)purin-9-yl]-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-yl] 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: [(2R,3S,5R)-5-[6-(6-aminohexylamino)purin-9-yl]-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-3-yl] 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
• 化学式: C₂₆H₄₃N₈O₁₄P₃S
• 分子量: 816.7
• InChiKey: LYXCFCHUMSNAEB-AQXOQHEOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -4.8
• 重原子数：
  52
• 可旋转键数：
  22
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  343
• 氢给体数：
  8
• 氢受体数：
  20

文献信息

• Modified Diguanylate Cyclase-Phosphodiesterase and Method for Enzymatic Production of Cyclic-diGMP
  申请人：NESBITT Natasha M.

  公开号：US20140170689A1

  公开（公告）日：2014-06-19

  The present invention provides a recombinant polypeptide comprising a first portion and a second portion, wherein the sequence of the first portion is fully identical to amino acids 1 to 248 of the sequence set forth as SEQ ID NO:1 and the sequence of the second portion is other than amino acids 249 to 511 of the sequence set forth as SEQ ID NO:1.