2-[Bis(2-hydroxyethyl)amino]ethanol;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 英文名称: 2-[Bis(2-hydroxyethyl)amino]ethanol;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
• 英文别名: 2-[bis(2-hydroxyethyl)amino]ethanol;2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid
• 化学式: C14H33N3O7S
• 分子量: 387.5
• InChiKey: FIMWKIAVMGCALV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.25
• 重原子数：
  25
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  153
• 氢给体数：
  5
• 氢受体数：
  10

文献信息

• [EN] OSSIFICATION-INDUCING COMPOSITION AND METHODS OF USE THEREOF<br/>[FR] COMPOSITION INDUISANT L'OSSIFICATION ET SES PROCÉDÉS D'UTILISATION
  申请人：UNIV GEORGIA

  公开号：WO2014093836A1

  公开（公告）日：2014-06-19

  Mesenchymal stem cells (MSCs) and uses thereof are provided. MSCs for inducing ossification and enhancing bone and/qr cartilage repair in a patient in need thereof are also provided. The method and compositions combine MSCs, at least one bone regeneration protein, such as bone morphogenetic protein (e.g. BMP-2), optionally in combination with additional cell growth factors including the components of a cell growth medium, further in combination with a biomaterial for delivery of the cells to the repair site in the patient are also provided.